Endocrine Abstracts

TIAR and TIA-1 are two closely related RNA-binding proteins, which possess three RNA recognition motifs (RMMs). These proteins are involved in several mechanisms of RNA metabolism, including regulation of mRNA translation. In cellular apoptosis continuously TIAR shuttled between the cytoplasm and nucleus.The aim of this study was to estimate expression of closely related mRNA binding proteins TIAR and TIA-1 in thyroid tissues from young patients with Gra...

The course of Graves’ disease is associated with the inflow of lymphocytes to the thyroid gland and dysregulation of the immune system characterized by reaction to thyroid antigens (peroxidase, thyroglobulin, TSH receptors and Na+/I− symporter).The aim of this study was to estimate sodium iodine symporter (NIS) and thyroid peroxidase (TPO) expression in thyrocytes which release cytokines INF-γ and IL-4 from young pat...