Endocrine Abstracts

Introduction: It has been shown that type 2 diabetes mellitus (T2DM) could affect bone metabolism through several mechanism and it may increases risk for osteoporosis. Glucose lowering therapies including metformin has also been reported to may effect on bone turnover. This study aimed to evaluate the effects of metformin therapy on bone resorption and formation markers in newly diagnosed patients with T2DM.Method/design: Study population consisted of 37...

Background: Studies on thyroid hormones in obese adult patients are contradictory. Moreover, little is known about the effect of weight loss on thyroid functions. Thus, we aimed to investigate thyroid hormone status, and possible effect of weight loss on thyroid hormones in obese patients.Methods: We study population consisted of 39 (35 female, 4 male) euthyroid obese patients with mean age 42.76±10.52 years. Of these 19 patients were morbid obese. ...

Introduction: Increasing evidence suggesting an integral role of vitamin D in skeletal muscle function. The relationship between muscle strength and vitamin D status has been investigated to some degree in older populations, however there has been very little research in younger adult women. This study aims to measure the effects of vitamin D on handgrip strength in young adult women.Method: A total of 141 healthy women with mean age of 33.8±6.8 wer...

Objective: Accumulating data suggests that post-prandial hypertriglyceridemia is important in the pathogenesis and progression of atherosclerosis, and thus cardiovascular diseases. We aimed to assess the acute effect of the orlistat vs placebo on post-prandial triglyceride (TG) level in diabetic and non-diabetic obese patients.Research Design and Methods: Study population consisted of 49 patients with obesity (25 non-diabetics, 24 diabetic). Patients wer...