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ea0067o31 | Oral Presentations | EYES2019

Onset of radiation-induced hypopituitarism in pituitary adenomas

Seejore K , Tudawe G , Mansoor T , Lynch JM , Orme SM , Phillips N , Loughrey C , Murray RD

Objective: Radiotherapy (RT) can achieve tumour control rates of over 90% in pituitary adenomas. The commonest toxicity of irradiation is hypopituitarism. The exact incidence is variable and requires long-term testing for deficiency of all hypothalamic-pituitary axes (HPA). The aim of this study is to determine the time to onset of individual hormonal deficiencies and establish a timeframe for endocrine testing post-RT.Methods: We retrospectively assesse...

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ea0065p282 | Neuroendocrinology | SFEBES2019

Onset of radiation-induced hypopituitarism in pituitary adenomas

Seejore Khyatisha , Tudawe Gireesha , Mansoor Tihami , Lynch Julie M , Orme Stephen M , Phillips Nick , Tyagi Atul , Flatley Michael , Loughrey Carmel , Murray Robert D

Introduction: Radiotherapy (RT) can achieve tumour control rates of over 90% in patients with pituitary adenomas. The commonest toxicity of irradiation is hypopituitarism. The exact incidence is variable and requires long-term intermittent testing for deficiency of all hypothalamic−pituitary axes (HPA). The aim of this study is to determine the time to onset of individual hormonal deficiencies and establish a time frame for endocrine testing during follow-up post-RT....

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Endocrine Abstracts

Onset of radiation-induced hypopituitarism in pituitary adenomas

Onset of radiation-induced hypopituitarism in pituitary adenomas

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