Endocrine Abstracts

Introduction: Schwannomas are tumors derived from myelin sheat of nerves which can displace and compress nerves causing pain, weakness and numbness. Very rarely they become malignant.Case report: Thirty-one years old patient was hospitalized at our Department to evaluate hypopituitarism. He was born at term by cesarean section, with hydrocephalus and did not start to breath spontaneously. A few months later, he was diagnosed with scoliosis thoracalis dup...

AI are incidentally discovered adrenal masses without any prior suspicions of adrenal disease. They are most frequently hormonally inactive, with arterial hypertension (AH) as a common finding.The aim was to determine upright and supine PR and ALD levels in patients with AI, normotensive and hypertensive.Two hundred and eight patients (148 women and 60 men, mean age 55.08±11.02 years, mean BMI 27.91±4.6 kg/m2) ...

Many studies have shown insulin resistance (IR) in majority of patients with adrenal incidentaloma. The euglycaemic hyperinsulinaemic glucose clamp technique is still considered as ‘golden standard’ for evaluation of insuline sensitivity. These methods are also complicated, labor-intensive procedure better for small research studies. Today, several surrogate indexes for insulin sensitivity were introduced such as: HOMA, QUIQI or G/IR. Some studies showed that QUIQI h...

Subclinical hyperthyroidism is a biochemical diagnosis defined with suppressed levels of TSH and normal levels of thyroid hormones. One of the main metabolic responses to thyroid hyperfunction is peripheral lipolysis and release of free fatty acids (FFA). The aim of this study was to compare levels of cholesterol, LDL, HDL and triglycerides in persons with subclinical hyperthyroidism to age and BMI matched euthyroid healthy control. We evaluated 45 persons in two groups: 1st g...

Subclinical hypothyroidism is a biochemical diagnosis defined with elevated levels of TSH and normal levels of thyroid hormones. The most common abnormality linked to this condition is hypercholesterolemia. The aim of this study was to search for MSy among the persons with subclinical hypothyroidism which was already proven to have hypercholesterolemia when compared to healthy control. MSy was identified in those with elevated triglycerides (Tgc), reduced HDL and elevated fast...

Several studies show that characteristics of metabolic syndrome are often seen in patients with adrenal incidentaloma. The aim of our study was to evaluate metabolic factors in these patients. 208 patients (148 female and 60 male, age 55.08±11.02 y’s and BMI 27.91±4.6 kg/m2) were admitted and biochemical, endocrine testing were performed. Lipid status: cholesterol 5.77±1.26 mmol/L, triglyceride 1.92±0.98 mmol/L. 113(55%) patients were hypert...

POF is a disease of unclear origin affecting women under age 40. They are at high risk of cardiovascular diseases (CVD).The objective of this study was to compare the lipid status and atherogenic indexes - total cholesterol/high density lipoprotein (TC/HDL) and low density lipoprotein/HDL (LDL/HDL) - of women with POF with healthy women of the same age and the same BMI.We evaluated 54 women in two groups. 1st group: 31 women with P...

Introduction: A rare cause of adrenal incidentaloma is congenital adrenal hyperplasia (CAH). Nonclassic CAH is one of the most frequent autosomal recessive disorders. Most cases of nonclassic CAH are never diagnosed due to very mild symptoms.Case report: A 62-year-old woman admitted at our Department for right adrenal incidentaloma sized 39×34×38 mm confirmed by MRI. She was asymptomatic. Her past medical history included stabile hypertension, ...

Introduction: In adults, the most common cause of obstructive sleep apnoea is obesity. Other causes are anatomical craniofacial bony abnormalities, neurologic syndromes, alcohol and sedatives use, hypothyroidism, acromegaly and rarely thyroid goitre. Untreated obstructive sleep apnoea can lead to serious complications, including cardiovascular diseases, accidents, and premature death.Case report: A 56-year-old patient was referred to a pulmologist due to...

Introduction: Primary thyroid lymphoma (PTL) presents between 2 and 8% of all thyroid malignancies. Rapidly enlarging neck mass, especially in women with Hashimoto’s thyroiditis should steer the diagnostic procedures in the way of PTL. The most common type is diffuse large B-cell lymphoma. Adrenal incidentaloma are incidentally discovered adrenal masses without prior suspicion of adrenal disease.Case report: A 71-year-old woman with an adrenal incid...