Endocrine Abstracts

Introduction: Graves’ disease and Hashimoto’s hypothyroidism are common thyroid diseases. However, occurrence of both clinical disorders one after the other in the same patient, is not common.Case report: In this article, we presented two hypothyroid patients who developed clinical thyrotoxicosis during levothyroxine treatment. Both patients were treated with levothyroxine for a long time. Due to occurrence of clinical hyperthyroidism, levothyr...

Objective: In chronic hypoparathyroidism, conventional therapy consists of oral calcium supplements and active vitamin D analogs but some patients cannot achieve treatment goals despite the high dose of oral calcium supplementation. Therefore, parathyroid gland transplantation and recombinant human PTH have been investigating as new therapeutic options. Calcium absorption from intestinal cells occurs by transcellular path and paracellular path. Transcellular absorption occurs ...

Introduction: Neutrophil/lymphocyte (N/L) ratio is considered as a sign of systemic inflammation in recent years. In our study, we aimed to investigate N/L ratio in hyperthyroid patients and healthy control group.Material & methods: A total of 121 hyperthyroid patients (71 patients with Graves’ disease and 50 patients with other causes of hyperthyroidism) and 40 healthy volunteers were enrolled. Complete blood count was obtained from both group ...

Pain is one of the few drawbacks of fine-needle aspiration biopsy (FNAB) in patients with nodular thyroid disease (NTD). Lidocaine/prilocaine cream, an eutectic mixture of local anesthetics (EMLA), is a frequently used topical anesthetic. Despite its well-documented efficacy for the relief of pain associated with other cutaneous procedures that involve needle insertion, the analgesic role of EMLA has not been previously reported in patients with NTD who are undergoing FNAB. Th...

Aim: To determine how serum procalcitonin (PCT) levels are affected in diabetic and diabetic nephropathic patients, it is important to determine whether PCT is indicative of an inflammation in these patients.Materials and methods: The study included 175 patients (75 diabetic nephropathy (group 1), 75 diabetic (group 2) and 25 non-diabetic nephropathy (group 3)) and 75 healthy volunteers. Serum and urine creatinine, serum high sensitive C- reactive protei...

Background: Glycemic control affects cardiovascular risk factors positively. The purpose of this study was to assess BNP levels in patients with poor control diabetes before specific treatment for hyperthyroidism and after glycemic regulation was achieved. The study was performed in a prospective design.Methods: The study population consisted of 79 consecutive diabetic patients with poor glycemic control. All subjects underwent transthoracic echocardiogr...

Increased plasma concentration of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, has been associated with cardiovasular risk factors. The aim of this study was evaluate plasma ADMA levels and subclinical atherosclerosis in patients with polycystic ovary syndrome (PCOS) and healty controls.Thirty-five patients with PCOS and age, body mass index (BMI) matced thirty-one healty subjects were included in the study.PCOS w...