Endocrine Abstracts

Oestrogen plays a major role in the regulation of bone turnover during the different phases of life. During puberty, the increase in oestrogen has a bisphasic effect on growth, stimulating the secretion of growth hormone and promoting the closure of the growth plate. It has an effect on modelling to stimulate endosteal apposition and inhibit periosteal apposition. It has an effect on bone remodelling, to decrease the rate of bone remodelling, and possibly to have an anabolic e...

Richard Eastell, Bone Metabolism Group, University of Sheffield, Sheffield, UK AbstractProfessor Eastell is Professor of Bone Metabolism at the University of Sheffield where he is also Director of Research for Medicine. He is the Research Dean for the School of Medicine and Biomedical Sciences, and Deputy Director of the Division of Clinical Sciences (North) at the University of Sheffield. He is also the Director for R...