Endocrine Abstracts

The differential diagnosis of post-partum thyrotoxicosis includes Graves' disease and post-partum thyroiditis(PPT). We present two cases which demonstrate the difficulty of interpreting 99mTc-pertechnetate scans in this setting. Case 1 is a 37 year-old lady who presented 5 months post-partum with a month history of palpitations, sweating and heat intolerance. Investigations revealed TSH < 0.01 mU/L, fT3 8.9 pmol/L (NR 10.5-22.7 pmol/L) and fT4 23.4 pmol/L (NR 3.5-6.5 pmol/)...

We present a case of Graves' disease in association with hemiagenesis of the thyroid gland.A 61 years old Caucasian man presented with light-headedness, proximal muscle ache and tiredness. Past medical history was unremarkable.Examination revealed a resting tachycardia. There was no goitre, and no evidence of Graves' ophthalmopathy.Thyroid profile revealed an FT4 of 42 picomoles per litre (11-24) and a TSH of...

Anti-thyroperoxidase autoantibodies (TPOAb) are one of the major secondary autoantibodies associated with AITD. Many endocrine hospital referrals are received for patients with elevated TPOAb levels without other disordered thyroid function tests.This study aimed to investigate the use of TPOAb testing in hospital practice, to determine whether the presence or absence of TPOAb indicates the existence of thyroid disease and the effect of the TPOAb result ...