Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2007) 14 P70

ECE2007 Poster Presentations (1) (659 abstracts)

Effect of L- carnitine supplementation on glycemic profile in patients with type 2 diabetes mellitus

Rahebeh Sakerhosseini , Alireza Rahbar , Avid Saadat , Amir hamzeh Pordal , Feroug azam Taleban & Banefsheh Golestan

National Nutrition and Food Technology Research Institute, Tehran, Iran.

Background: It has been thought that L-carnitine is effective in improving insulin-mediated glucose disposal either in healthy subjects or in type 2 diabetic patients,and carnitine plays an important role in diabetes mellitus omplications (cardiovascular disease).

Objective: We designed this study to investigate the effects of oral L-carnitin administration on fasting plasma glucose (FPG) and glycosylated hemoglob (HbA1c), in patients with diabetes mellitus type II.

Materials and methods: The effect of L-carnitine on FPG and lipid parameters was investigated in 22 male and 14 female type II diabetic patients, mean age±SD was 51.3±3.7 years. The patients were randomly divided into 2 groups (i.e. test and control groups). One gram of L-carnitine or placebo was given orally three times a day to the test and control groups respectively for a period of 12 weeks.

Results: Fasting plasma glucose in the test group decreased significantly from 143±35 mg/dl to 130±35 mg/dl (P=0.03. There were no significant changes in HbA1c, between the two groups.

Conclusion: L-carnitine significantly lowers fasting plasma glucose in type II diabetic patients

Article tools

My recent searches

No recent searches.