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Endocrine Abstracts (2007) 14 P75


Virgen Macarena Hospital, Seville, Spain.

Objective: To study if the use of continuous glucose monitoritation systems in real time (GUARDIAN REAL TIME®) in the diabetic patients could improve the metabolic control.

Material and method: 15 type 1diabetic patients studied (age: 33.8±13.40, years of evolution: 17.06±11.32) in intensive treatment (5 multidoses, 10 insulin pump) which were made one first blind 4 days long monitoritation to them, PERIOD 1 (P. BLIND) with sensor CGMS Gold®. Next it was made another monitoritation with a real time system with glycemia and alarms of hyperglycemia and hypoglycemia, GUARDIAN RT®, PERIOD 2 (P. Real time). These 2 monitoritations were consecutive in each patient, establishing in the second period the levels of alarm of hypoglycemia in 50 mg/dl and hyperglycemia in 200 mg/dl. We studied in both periods: Average glycemia Glycemia Variability, Percentage of time in hiperglycemia (>180), normoglycemia and hipoglycemia (<70). A non-parametric test for matched up data was made (Wilcoxon)

Average glucose157.17±34.30 (110–224)137.49±21.99 (115–203)0.053
Variability73.72±19.60 (38–103)48.23±13.20 (25–75)<0.005
% High32.56±19.25 (7.0–75.0)19.90±13.87 (1.23–56.03)<0.05
% Euglucemia55.49±17.79 (25.0–86.0)74.98±14.22 (43.97–98.77)<0.005
% Low11.94±8.04 (0.00–29.00)5.10±5.16 (0–17.00)<0.005

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