Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2007) 14 P77

1National Research Centre of Endocrinology, Moscow, Russia; 2Moscow Sechenov Medical Academy, Moscow, Russia.


Aim: To study prevalence of foot complications in patients on dialysis therapy and evaluate the role the haemodynamic changes during dialysis procedure in development of foot problems.

Methods: 109 dialysis patients, mean age 49 years. 60 of them had diabetes mellitus (DM): 29 on haemodialysis (HD), 31 on peritoneal dialysis (PD). Non-diabetic patients (NDM): 24 HD, 25 PD.

Vascular status: doppler, photoplethysmography. Polyneuropathy: NDS. Monitoring of BP: during and after dialysis (follow-up period 14 months).

Results: Peripheral vascular disease (PVD) was associated with DM (16 DM vs. 1 NDM). Polyneuropathy: 51 DM, and in 7 NDM.

Ulcers were diagnosed only in DM patients (prevalence 25%). The number of patients with diabetic ulcers was increased after starting dialysis therapy (from 4 to 12) and it was due to increasing neuroischemic ulcers (from 0 to 8, P=0,016).

Transient intra- and postdialysis hypotension (TH) was determined in 15 HD, 5 PD. This group had significant fall of pressure in toe arteries during TH. Neuroischemic ulcers were frequently diagnosed in the group with PVD and HD, than with PVD and without HD; P=0,001.

Conclusions: Diabetic patients on dialysis therapy have high risk of neuroischemic ulcers. TH can intensify PVD and provoke neuroischemic ulcers.

Article tools

My recent searches

No recent searches.

My recently viewed abstracts