Currently there are only rare data on the prevalence of thyroid dysfunction in hospitalized patients. Therefore, we prospectively measured TSH values in patients admitted to a clinic of general internal medicine in an area of moderate iodine deficiency.
In 1011 patients (mean age 66.2 years; median 72 years) TSH was consecutively evaluated.
The mean TSH was 1.74 μU/ml (range 0.0093.3); median 1.1 μU/ml.
In 732 patients (74.4%) TSH was within the normal range (0.352.8 μU/ml) 120 patients (11.9%) had TSH levels above 2.8 μU/ml.
About 139 patients (13.7%) had TSH levels below 0.35 μU/ml. Among those 139 patients 51 patients had TSH values below 0.1 μU/ml.
There was a negative correlation of age and TSH (P<0.05).
We found pathologic TSH values in 25% of patients admitted to a clinic of general internal medicine. Whether these alterations are related to true thyroid dysfunction or are influenced by the underlying illness needs further evaluation.
03 - 07 May 2008
European Society of Endocrinology