Introduction: We aimed to evaluate the relationship between platelet count and metabolic risk factors in over weight and obese women in Turkish women.
Methods: Over weight (BMI>25 kg/m2) 665 and obese (BMI>30 kg/m2) 4609 women were enrolled into the study. The patients were divided into three group according to the platelet count (PLT), Group I (n=1724) consist of serum PLT≤245×103, group II (n=1787) consist of PLT 245×103 to 300×103 and, group III (n=1763) consist of PLT >300×103 μl. The groups were compared for metabolic risk markers.
Results: Body weight, BMI and body fat mass, waist circumference, sagital waist, fasting glucose, insulin, HOMA, A1c, total cholesterol, LDL-cholesterol, triglycerides, hs-CRP, ESR and, systolic and diastolic blood pressures were significantly high in Group III compared to Group I and Group II (P<0.05).
|Group I (n=1724)||Group II (n=1787)||Group III (n=1763)||P value|
|Waist circumference (cm)||96.72±14.98||99.05±14.35||102.05±20.64||<0.001|
|Saggital waist (cm)||23.61±4.11||24.49±4.42||25.50±4.29||<0.001|
|Insulin (uIU/ml log)||12.45±12.00||12.98±9.72||15.20±13.49||<0.001|
|Triglicerides (mg/dl log)||137.13±110.95||143.68±124.63||151.20±105.28||0.015|
|Systolic DB (mmHg)||126.83±24.86||127.55±23.30||130.89±23.51||<0.001|
|Diastolic DB (mmHg)||80.97±13.55||81.51±13.59||82.91±14.47||<0.001|
Conclusion: The data obtained from this study indicates that high PLT count is associated with several metabolic risk markers. Platelet count can be suggested as a risk marker for atherosclerotic disease in overweight and obese women.