Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology BES 2010

Plenary Lecturers’ Biographical Notes

Clinical Endocrinology Trust Lecture

ea0021pl8 | Clinical Endocrinology Trust Lecture | SFEBES2009

Ubiquitination: the ‘Kiss of Death' for human growth

Clayton Peter E , Hanson Dan , Murray Philip , Sud Amit , Black Graeme

Ubiquitination (Ub) is the process that controls the level and activity of cellular proteins. Mono-ubiquitination of a protein alters its function, while poly-ubiquitination targets a protein for degradation (as the ‘kiss of death’). Alterations in the Ub system are associated with a wide range of disease, e.g. cancer, neurological diseases and viral infection.Disorders of growth where the phenotype is primarily short stature are usually caused...

ea0021pl8biog | Clinical Endocrinology Trust Lecture | SFEBES2009

Clinical Endocrinology Trust Lecture

Clayton P E

P E Clayton, Endocrinology and Diabetes Group, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK AbstractPeter Clayton is Professor of Child Health and Paediatric Endocrinology in the Faculty of Medical and Human Sciences at the University of Manchester. He is an honorary consultant at the Royal Manchester Children’s Hospital and at the Christie Hospital and is the Director of t...