Endocrine Abstracts

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Constitutional delay of growth and puberty (CDGP) is the most common diagnosis among males and females with pubertal delay, but it can be diagnosed only after exclusion of other underlying conditions. Most of the boys with delayed puberty have CDGP, but about 5–10% have hypergonadotropic hypogonadism (including Klinefelter), 10% have permanent hypogonadotropic hypogonadism (including Kallmann syndrome and idiopathic hypogonadotropic hypogonadism), and 10% have a transient...