Searchable abstracts of presentations at key conferences in endocrinology
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15th International & 14th European Congress of Endocrinology

Symposia

Early Development and Treatment of PCOS

ea0029s62.1 | Early Development and Treatment of PCOS | ICEECE2012

Early hormonal abnormalities in children born to women with PCOS

Sir-Petermann T.

Polycystic ovary syndrome (PCOS) is a common endocrine-metabolic condition with a strong familial component suggesting a genetic susceptibility. During pregnancy, PCOS mothers offer an altered intrauterine environment which may also be implicated in the origin of this syndrome, and could determine endocrine/metabolic disturbances in their offspring (boys and girls) that may persist later in life. We have evaluated this possibility studying sons and daughters of PCOS mothers fr...

ea0029s62.2 | Early Development and Treatment of PCOS | ICEECE2012

Early development and pubertal prevention of polycystic ovary syndrome

de Zegher F. , Ibanez L.

PCOS (defined by NIH, Rotterdam or AES criteria) is traditionally viewed as an ovarian disorder that appears in adolescence and may lead to metabolic complications in adulthood. Emerging evidence, however, indicates that PCOS is primarily a disorder of adipose-tissue hyperexpansion that may originate in early life, develop across childhood and puberty, and advance into end-stage disease (including ovulatory dysfunction and ovarian androgen excess) by adolescence. Prepubertal m...

ea0029s62.3 | Early Development and Treatment of PCOS | ICEECE2012

Hyperandrogenism in obese girls: what is the significance?

McCartney C.

Polycystic ovary syndrome (PCOS) is marked by (primarily ovarian) hyperandrogenemia and ovarian dysfunction. In many cases, PCOS first manifests during adolescence, and both peripubertal hyperandrogenemia and obesity are considered risk factors for the development of PCOS. Many, but not all, pubertal girls with obesity – including those in early puberty – exhibit relative hyperandrogenemia. However, the causes of peripubertal obesity-associated hyperandrogenemia, and...