ECE2013 Poster Presentations Thyroid (non-cancer) (100 abstracts)
Introduction: Changes in thyroid function have significant impact on the cardiovascular system.
Methods: In a group of 37 subjects the level of thyroid hormones FT4, FT3, and TSH were measured. Then carried out short-term analysis for 30 min measureing variability of blood pressure with non-invasive TASK FORCE monitor. Registered data were analyzed by spectral analysis of variability. Statistical analysis were done by Pearson correlation model.
Results: The analysis of the parameters of the variability of systolic blood pressure (SBP), we confirmed that FT4 positively correlated with parameters of spectral analysis of variability of systolic blood pressure: sBP LF; sBP LF/HF (P<0.05), sBP LF, sBP PSD (P<0.001). Discovered a negative correlation with sBP HF nu (P<0.05). FT3 is positively correlated with parameters of systolic blood pressure variability: sBP LF nu, sBP LF, sBP PSD, sBP LF/HF (<0.05). TSH is positively correlated with SBP HF nu (r=0.4379) and HF SBP (P<0.05).
The analysis of correlation with thyroid hormone parameters of diastolic blood pressure variability has been found for FT3 negatively correlated with DBP HFnu (P<0.5) and positive correlation with DBP LF (P<0.05).
Conclusion: Our study demonstrates a significant correlation between thyroid hormones with a systolic blood pressure and less important correlation with parameters of diastolic blood pressure variability. The analysis of variability of systolic blood pressure observed a positive correlation between FT4 and FT3 with parts of the spectrum of low frequency (sympathetic activity) and total spectral power (PSD). FT4 and FT3 were in negative correlation with parts of the spectrum of high frequency (parasympathetic). TSH correlated positively with the parasympathetic nervous system.
Analysis of variability of diastolic blood pressure registered a small number of significant correlations and FT3 negatively correlated with DBP HFnu (P<0.5) and positive correlation with DBP LF (P<0.05).