Searchable abstracts of presentations at key conferences in endocrinology
Endocrine Abstracts (2014) 34 P315 | DOI: 10.1530/endoabs.34.P315

SFEBES2014 Poster Presentations Reproduction (26 abstracts)

Protective role of Nigerian honey on sperm indices and testis in sucrose-fed rat

Oluwakemi Oyelowo 1 , Daniel Adekunbi 2 & Kayode Dada 1

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1University of Lagos, Lagos, Nigeria; 2Babcock University, Ilishan-ReMO, Nigeria.


This study aimed at investigating the effect of high sucrose diet on male reproductive function and if Nigerian honey could exert a protective role. Twenty-four rats were randomly divided into four equal groups of six animals and given water (control); honey (H); high sucrose solution (30%w/v) (HSS); and both high sucrose solution (30%w/v) and honey (HSS+H). Each rat on honey received a daily dose of 10 ml honey/kg per 5 ml of distilled water. Food intake, body weight, organ weight, fasting blood glucose, LH, FSH, testosterone and sperm functions were assessed. This revealed that sperm motility (P<0.05) and count increased in the HSS+H and H-fed rats compared with HSS fed and control rats. Head and tail abnormalities sperm were also significantly reduced in the H fed rats (P<0.05). MDA level in the liver and not in the testes was significantly increased in the HSS fed rats compared with control while SOD activity was significantly increased in HSS+H rats compared with the HSS fed rats. The results indicate that sucrose feeding impact negatively on sperm function while Nigerian honey supplementation confers protective function on male reproduction.

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