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Endocrine Abstracts (2014) 35 P968 | DOI: 10.1530/endoabs.35.P968

Çanakkale Onsekiz Mart University, Çanakkale, Turkey.

Objective: Thyroid diseases are among the most common endocrine disease and with a prevalence of 1.2%. Thyroid hormones have several effects on cardiovascular system. Many studies showed the association between hyperthyroidism and acute ischemic heart disease with conflicting results. Epicardial adipose tissue (EAT) thickness is a marker of atherosclerosis and independent predictor of coronary artery disease. In this study, we aimed to evaluate the EAT thickness in patients with overt hyperthyroidism (OH).

Materials and methods: Thirty newly diagnosed untreated OH patients and 44 control subjects were included in the this study. EAT thickness and carotid intima media thickness (CIMT) were measured by echocardiography.

Results: EAT thickness and CIMT were higher (4.31±1.12 mm, 3.11±0.84 mm, P<0.001; 0.62±0.17 mm, 0.50±0.11 mm, P<0.01 respectively) in OH patients than in healthy subjects.

Conclusion: In conclusion, EAT thickness was higher in OH patients, therefore EAT thickness together with CIMT may be used as markers of early atherosclerosis in OH patients which had higher cardiovascular mortality than normal population.

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