Searchable abstracts of presentations at key conferences in endocrinology
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17th European Congress of Endocrinology

Guided Posters

Thyroid – nodule

ea0037gp.25.01 | Thyroid – nodule | ECE2015

Long-term results of US-guided high-intensity focused ultrasound treatment of benign thyroid nodules

Kovatcheva Roussanka , Vlahov Jordan , Stoinov Julian , Zaletel Katja

Introduction: Thyroid nodules can be detected by ultrasound (US) in 20–30% of unselected populations. Various non-surgical techniques such as laser and radiofrequency ablation have been developed to reduce thyroid nodule size. High-intensity focused ultrasound (HIFU) ablation is a new, non-invasive method that has been shown recently. The aim of our study was to assess the long-term efficacy and safety of US-guided HIFU treatment of benign solid thyroid nodules.<p cla...

ea0037gp.25.02 | Thyroid – nodule | ECE2015

Thyroid hormones influence the expression of TNF-related apoptosis-inducing ligand

Bernardi Stella , Bossi Fleur , Giudici Fabiola , Secchiero Paola , Zauli Giorgio , Fabris Bruno

Background: There is growing evidence supporting TNF-related apoptosis-inducing ligand (TRAIL) involvement in weight and body composition regulation, which are classically influenced by thyroid hormones. This study aimed at investigating the relationship between thyroid hormones and TRAIL.Methods: Circulating TRAIL was measured in 40 controls, 40 hyperthyroid, and 25 hypothyroid patients before and after their respective treatments. In the same patients ...

ea0037gp.25.03 | Thyroid – nodule | ECE2015

Malignancy rate in thyroid nodules with AUS/FLUS cytology in a Cancer Center (Bethesda System for Reporting Thyroid Cytopathology 2009)

Nunes Joana Menezes , Martins Raquel , Santos Jacinta , Martins Teresa , Moniz Ana Paula , Ilheu Olga , Figueiredo Paulo , Rodrigues Fernando

Introduction: The Bethesda System for Reporting Thyroid Cytopathology is the standard for interpreting fine-needle aspiration (FNA) and created a new diagnostic category (III): ‘atypia of undetermined significance/follicular lesion of undetermined significance’ (AUS/FLUS). The risk of malignancy for this category has been ascribed of 5–15% but the real malignancy rate remains unclear and plays a key role to define appropriate management.Ob...

ea0037gp.25.04 | Thyroid – nodule | ECE2015

Evaluation of benign thyroid nodules in a 10-year follow-up

Silva Joao , Ivo Catarina , Marcelino Mafalda , Simoes Helder , Lopes Luis , Passos Dolores , de Castro Joao Jacome

Introduction: American Thyroid Association recommends that benign thyroid nodules should be revaluated 6–18 months after initial FNA and in case of stability the follow-up should be 3–5 years. However there isn’t any consensus about the periodicity of the follow-up.Aim: To evaluate the nodules in terms of function, size and malignancy in a 10-year follow-up.Methods: Retrospective study of 347 patients (543 benign thy...

ea0037gp.25.05 | Thyroid – nodule | ECE2015

Sox9 is expressed in thyroid follicular cells and regulates the expression of thyroid differentiation genes

Lopez-Marquez Aristides , Carrasco-Lopez Carlos , Santisteban Pilar

The transcription factor Sox9 is a member of the HMG-box-DNA binding family essential for chondrocyte differentiation, sexual determination, and the maintenance of the stem/progenitor cells in several tissues. Furthermore, Sox9 is involved in the development of endoderm-derived-organs. Owing to the endodermic origin of the thyroid, we proposed to study the expression of Sox9 in thyroid follicular cells and its regulation by TSH and TGFβ, two main factors involved in thyro...

ea0037gp.25.06 | Thyroid – nodule | ECE2015

Clinical outcome of thyroid nodules characterised as atypia of undetermined significance or follicular lesion of undetermined significance (The Bethesda System for Reporting Thyroid Cytopathology) after fine-needle aspiration

Garcia Fernando , Tome Mariana , de Pinillos Guillermo Martinez , Cuellar Eyvee Arturo , Mendez Mariola , Garcia de Quiros Juan Manuel , Pena Ignacio Fernandez , Lopez Ignacio Fernandez , Hidalgo Juana , Rivas Margarita , Duran Santiago , Cozar Maria Victoria

Introduction: ‘Atypia of undetermined significance (AUS) or follicular lesion of undetermined significance’ category is established by The Bethesda System for Reporting Thyroid Cytopathology because of the necessity to report those thyroid fine-needle aspiration (FNA) results that are not easily classified into the benign, suspicious or malignant categories. In most cases, a repeated FNA results in a more definitive interpretation. Estimated risk of malignancy for an...

ea0037gp.25.07 | Thyroid – nodule | ECE2015

Malignancy risk stratification of thyroid nodules by TIRADS; correlation with cytological results

Martinez Antonio J , Hernando Virginia , Garcia Clara , Torres Alberto , Martin Tomas

Introduction: Knowing that only in 5–15% of FNABs the pathological analysis shows malignancy, enhance diagnostic accuracy is needed. The use of the TIRADS score and a revised version proposed by the British Thyroid Association (BTA) intend to determine if a FNAB should be performed or not in the evaluation of nodular goitre.Objective: To determine whether an adequate correlation is present between the risk category assigned to the nodules studied un...