Endocrine Abstracts

Introduction: Early detection of carbohydrate and fat metabolism disorders in women with polycystic ovary syndrome allows the early prevention of cardiovascular diseases and type II diabetes.

Aim: The purpose of this study was to assess the selected metabolic indicators and anthropometric measurements in two groups of women: metabolically healthy polycystic ovary syndrome (MH-PCOS) and metabolically unhealthy PCOS (MU-PCOS).

Materials and methods: Cross sectional study was conducted in a group of 44 women hospitalized in the endocrinology department who met the Rotterdam criteria of PCOS syndrome. Tested women were divided into a MH-PCOS (VAI <1.675) group and a MU-PCOS (VAI >1.675) group. Body composition was analyzed via bioelectrical impedance analysis (BIO). During the statistical analysis it was assumed that α=0.05.

Results: Examined women, was at age 18–38 years (26.52±5.73). The average age of the MH-PCOS group was 26 (22.5–31) and 25.27±5.57 (P>0.05) in the MU-PCOS group. The study showed statistically significant differences between the MU-PCOS group and the MH-PCOS group in term of values: body mass (87.04±19.12 vs 61.3 (54.9–70.25); BMI indicator (32.61±6.44 vs 22.85 (20.7–25.25); P=0.001), waist circumference (100.5±16.03 vs 79.52±11.9; P<0.01), serum triglyceride concentration (1.6 (1.37–2.03) vs 0.81±0.26; p=0.001), HOMA IR (2.72±1.21 vs 1.66 (1–2.5); P=0.0387). Statistically, the average value of HDL cholesterol was significantly lower in the MU-PCOS group than in the MH-PCOS group (1.16±0.09 vs 1.83±0.39) (P<0.01). In the study, a statistically significant positive correlation was noticed between the Visceral Adiposity Index (VAI) value and the body mass (r=0.69), the insulin level (r=0.46) and the HOMA IR indicator (r=0.33) (P<0.05 for all).

Conclusion: Visceral Adiposity Index may be an easy and effective tool to assess metabolically unhealthy women with PCOS in the daily diet and medical practice.