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Endocrine Abstracts (2015) 37 EP507 | DOI: 10.1530/endoabs.37.EP507

1Department of Endocrinology and Metabolism, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey; 2Division of Rheumatology, Adana Numune Training and Research Hospital, Adana, Turkey; 3Department of Internal Medicine, Faculty of Medicine, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey.


Aim: Diabetes mellitus is a chronic metabolic condition characterised by persistent hyperglycaemia with resultant morbidity and mortality related primarily to its associated microvascular and macrovascular complications In this study our aim was to investigate the prevalence of the most frequently occurring hand complications in 1000 type 2 diabetes mellitus (T2DM) patients.

Material and methods: 297 patients (mean age 52.13±9.37 years, 190 women and 107 men) who had T2DM were included as a preliminary in this study. The presence of cheiroarthropathy, Dupuytren’s contracture, tinnel sign, and tendinitis was assessed. All patients were evaluated also by the Rheumatology Division. Diabetic retinopathy was assessed by direct ophthalmoscopy. Urinary albumin excretion was determined in at least two 24 h urine samples.

Results: The mean diabetic duration was 7.71±6.28 years. Dupuytren’s contracture was present in 7.7%, cheiroarthropathy in 11.1%, tinnel sign in 19.5%, and tendinitis in 4.4%. Retinopathy was present in 15.5% and nephropathy in 18.2%. Mean HbA1c was 8.58±2.03. Mean fasting glucose was 174.6±69.22 mg/dl. The relationship between these complications and patients’ age, sex, duration of diabetes, and glycaemic control was also analysed. There was positive correlation between age and cheiroarthropathy and dupuytren’s contracture (P=0.01, r=193 and P=0.000, r=248 respectively). There was positive correlation between diabetic duration and diabetic retinopathy (P=0.000, r=216). There was positive correlation between diabetic duration and cheiroarthropathy (P=0.044, r=117). There was positive correlation between diabetic nephropathy and tinnel sign (P=0.005, r=164).

Conclusions: Some musculoskeletal disorders are more prevalent in T2DM patients and this may be associated with duration of diabetes. Also the hand abnormalities were associated with the diabetic complications. Long-term prospective randomised controlled trials on preventing musculoskeletal complications and disability in diabetics are needed.

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