ECE2016 Eposter Presentations Thyroid (non-cancer) (120 abstracts)
Assessment of 25-Hydroxy vitamin D level in pre- and postmenopausal women with euthyroid Hashimoto’s thyroiditis
Muge Bilge 1 , Mine Adas 2 , Aylia Yesilova 1 & Aysen Helvaci 1
1Internal Medicine Clinic, Okmeydani Training and Research Hospital, Istanbul, Turkey; 2Endocrinology Department of Internal Medicine Clinic, Okmeydani Training and Research Hospital, Istanbul, Turkey.
Objective: Hashimoto’s thyroiditis is a common autoimmune disorder. A few studies have analyzed the association between serum vitamin D levels and Hashimoto’s thyroiditis and available data remains inconclusive. The aim of this study was to evaluate the association between serum 25-Hydroxy vitamin D levels in pre- and postmenopausal woman with Hashimoto’s thyroiditis.
Methods: We evaluated 120 premenopausal women with euthyroid Hashimoto’s thyroiditis (Group 1), 51 postmenopausal women with Hashimoto’s thyroiditis (Group 2), and the control groups consisted of 102 (74 premenauposal and 28 postmenauposal) age matched healthy subjects; who applied to our outpatient clinic of the internal medicine and endocrinology department. Anti-thyroid peroxidase (TPOAb) and anti- thyroglobuline (TGAb) antibody were positive in all patients. Serum thyroid-stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), 25-Hydroxy vitamin D and parathyroid hormone (PTH) levels were measured.
Results: In the group 1 the mean vitamin D level was 12.46 μg/L (SD±12.34), compared to 19.467 μg/L (S.D.±8.19) in the control group for premenopausal women, P=0.02 (Table 1). In the group 2 the mean vitamin D level was 18.46 (S.D.±10.97) μg/L, compared to 23.12 μg/L (S.D.±8.60) in the control group for postmenopausal women (Table 2).
| Group 1 (n=120) | Control (n=74) | P | |
| Age | 36.41±7.8 | 36.59±7.86 | NS |
| TSH (μIU/ml) | 2.86±1.45 | 1.90±0.92 | <0.001 |
| Free T4 (ng/dl) | 1.15±0.34 | 1.13±0.13 | NS |
| Free T3 (ng/dl) | 2.96±0.51 | 2.96±0.42 | NS |
| TPOAb (IU/ml) | 288.32±290.78 | 8.82±5.56 | <0.001 |
| TGAb (IU/ml) | 285.84±604.72 | 16.01±11.29 | <0.001 |
| Vitamin D (μg/l) | 12.46±12.34 | 19.47±8.19 | 0.02 |
| PTH (ng/l) | 46.80±17.30 | 49.15±18.03 | NS |
| (NS; Not Significant). | |||
| Group 2 (n=51) | Control (n=28) | P | |
| Age | 54.2±5.65 | 53.28±5.31 | NS |
| TSH (μIU/ml) | 2.74±2.05 | 2.47±1.11 | NS |
| Free T4 (ng/dl) | 1.14±0.25 | 1.13±0.15 | NS |
| Free T3 (ng/dl) | 2.99±0.46 | 3.01±0.39 | NS |
| TPOAb (IU/ml) | 329.81±326.51 | 7.89±2.83 | <0.001 |
| TGAb (IU/ml) | 381.32±721.65 | 20.50±17.11 | <0.01 |
| Vitamin D (μg/l) | 18.46±10.97 | 23.12±8.60 | NS |
| PTH (ng/l) | 52.16±23.25 | 51.18±18.34 | NS |
| (NS; Not Significant). | |||
Keywords: Hashimoto’s thyroiditis, 25-Hydroxy vitamin D, pre- and postmenopausal woman
Article tools
My recent searches
My recently viewed abstracts
Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
© Bioscientifica 2024 |
Privacy policy |
Cookie settings
BiosciAbstracts
Bioscientifica Abstracts is the gateway to a series of products that provide a permanent, citable record of abstracts for biomedical and life science conferences.
Find out more