Background and aims: To evaluate the evolution of thyroid cancer epidemiological characteristics from 2004 to 2014.
Materials and methods: Retrospective analysis of histological data from thyroidectomies performed in our hospital in the period 20042014.
Results: From 2004 to 2014, 2725 thyroidectomies (women 81% vs men 19%) were performed in our hospital. In 1083 of these (40%) histologic examination revealed thyroid cancer.
Thirty-four percent of all cancers were diagnosed from 2004 to 2010, while this percentage arises to 66% during the last four years. Median age at diagnosis was 49.2 years.
In almost half (43.7%) of thyroid cancer patients, Hashimotos thyroiditis coexisted.
Forty-eight percent of cancers were multifocal, whereas in the remaining 52% there was found a single focus on histologic examination. In the multifocal cancers, median maximum focus was less than 1 cm in 68.7% and >1 cm in 31.3%.
Invasion of thyroid capsule was reported in 36.7% of all cancers.
A total of 26.5% showed extrathyroidal extension, independently of the maximum focus size.
It is interesting to report that frequency of invasive behaviour is increasing from 2008 to 2014. Histologic types: papillary 94%, follicular 2.5%, medullary 2.8%, Hurtle-cell 0.6%, anaplastic 0.1%.
Conclusions: i) The percentage of thyroid cancers is gradually increasing per year in the period studied, which could mean:
more targeted pre-surgery diagnostic evaluation and referral for thyroidectomy.
a possible real increase in thyroid cancer frequency.
ii) Maximum frequency of thyroid cancer in middle aged patients, mainly women.
iii) Coexistence of Hashimotos thyroiditis in almost 50% of cases.
iv) Independently of maximum thyroid cancer focus, increased frequency of invasive behaviour is reported during the last 5 years.