Endocrine Abstracts

Drug-induced hyperprolactinaemia is a frequently encountered clinical entity due to the large number of commonly prescribed medications that may influence prolactin secretion. Anti-psychotics, anti-depressants and anti-emetics are most frequently culpable, predominantly due to inhibitory effects on hypothalamic-pituitary dopamine signalling. The onset and severity of hyperprolactinaemia may be highly variable, and individuals may harbour typical symptoms (e.g. galactorrhoea, a...

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Hypercalcaemia is a moderately common condition accounting for approximately 1% of all acute general medical presentations. Guidance on emergency management of the hypercalcaemic patient, aimed primarily at the generalist and at guiding initial stages of management has recently been developed by the society (https://www.endocrinology.org/policy/docs/13-02_EmergencyGuidance-Acute...

All patients with phaeochromocytoma should undergo surgical resection by an experienced surgeon. Surgery should only be carried out after adequate medical preparation to minimize catecholamine-related adverse events. Pre-operative pharmacologic treatment is aimed at controlling hypertension and tachycardia, and volume expansion. This session will summarise the current practice in the medical management of patients with phaeochromocytoma at Hammersmith Hospital....

Critical illness is associated with significant morbidity and mortality. The changes in the hypothalamo-pituitary-adrenal (HPA) axis that occur during critical illness are complex and whilst early studies had suggested improved outcome in patients with septic shock treated with parenteral glucocorticoids, this was not endorsed in subsequent studies and it remains a highly controversial area.In patients with underlying pituitary or adrenal disease where c...