Searchable abstracts of presentations at key conferences in endocrinology
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Society for Endocrinology BES 2016

Brighton, UK
07 Nov 2016 - 09 Nov 2016

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07 Nov 2016 to 09 Nov 2016 Brighton, UK Further information

Plenary Lectures

British Thyroid Association Pitt-Rivers Lecture

ea0044pl8 | British Thyroid Association Pitt-Rivers Lecture | SFEBES2016

Thyroid hormone: far reaching consequences of local actions

Williams Graham

Thyroid hormone action in individual target tissues is a complex and tightly regulated process. Thyroid hormones (thyroxine, T4 and triiodothyronine, T3) enter target cells via active transport mediated by specific transporter proteins. T4 is a biologically inactive pro-hormone that is converted to the active hormone T3 by removal of a critical iodine atom. Two iodothyronine deiodinase enzymes (Dio2 and Dio3) are expressed in periphe...