Searchable abstracts of presentations at key conferences in endocrinology
Previous issue | Volume 49 | ECE2017 | Next issue

19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

Card image cap
20-23 May 2017, Lisbon, Portugal Further information

Eposter Presentations: Interdisciplinary Endocrinology

Clinical case reports - Thyroid/Others

ea0049ep762 | Clinical case reports - Thyroid/Others | ECE2017

Multiple autoimmune syndrome: about six observations

Mrabet Soumaya , Hammami Aya , Nour Elleuch , Hanen Jaziri , Aida Ben Slama , Ahlem Braham , Salem Ajmi , Ksiaa Mehdi , Ali Jmaa , Elhem Ben Jazia

Introduction: Autoimmune disorders are known to be more frequent in women and often associated each others, but it is rare to see multiple autoimmune diseases in a single patient. Multiple autoimmune syndrome (MAS) is defined as the combination of at least three autoimmune diseases in the same patient. The pathogenesis of MAS is not known. Genetic, infectious, immunologic and psychological factors have all been implicated in its development.Observations:...

ea0049ep763 | Clinical case reports - Thyroid/Others | ECE2017

Endocrine complications in a female patient with β-thalassemia major following bone marrow transplantation

Cima Luminita Nicoleta , Lambrescu Ioana Maria , Stejereanu Lavinia , Colita Anca , Fica Simona

We report the case of a 14-year-old female patient with β-thalassemia major (β-TM) that presented numerous endocrine complications following bone marrow transplantion (BMT). The patient was admitted in our department for endocrine evaluation 3 years after BMT. She was diagnosed with β-TM at 1 year of age and received chronic blood transfusions and oral chelating therapy until 2012 when BMT was performed. The patient developed acute skin and intestine graft-versu...

ea0049ep764 | Clinical case reports - Thyroid/Others | ECE2017

Association of Basedow disease with pernicious anemia: a case report

Diaconescu Mihai Radu , Diaconescu Smaranda

Introduction: Immunologic background often present different association of two or more autoimmune diseases. However the coexistence of Basedow disease (BD) – the prototype of these disorders - with pernicious anemia (PA), sometimes as a component of pancytopenia, is rarely described. Between 50 patients operated on immunologic hyperthyroidism in a 20 years period only one case related this uncommon combination.Case report: AB, a 46-year-old woman w...

ea0049ep765 | Clinical case reports - Thyroid/Others | ECE2017

Chronic hyponatremia caused by Thiazide diuretic: A case report

Kermaj Marjeta , Ylli Dorina , Zeqja Anisa , Hoxha Violeta , Fureraj Thanas , Sanxhaku Renta , Muco Ermira , Shkurta Adela , Demaj Enalda , Ylli Agron

Introduction: Hyponatremia (defined as a serum sodium level <135 mmol/l), is seen in in 15–30% in hospital setting, especially in intensive care units. Certain drugs (e.g.Thiazides diuretics) used in everyday clinical practice, may induce hyponatremia, more frequently in elder women.Case report: A 76-year-old woman presented at emergency unit with complaints: physical weakness, nausea, vomiting, extreme fatigue and abdominal pain. She was under ...

ea0049ep766 | Clinical case reports - Thyroid/Others | ECE2017

Raynaud phenomenon in a young PCOS patient

Leczycka Martina Eva , Ohrman Johannes , Maksoud Hisham

Polycystic ovarian syndrome presents in 4–8% of women worldwide, making it the most common reproductive age endocrinopathy. Rheumatological concomitant diseases are extremely rare in PCOS patients, especially Raynaud’s phenomenon. Condition that, lowers the quality of life in patients, suggesting hormonal imbalances despite years of treatment. Studies show that oestrogen plays a role in the vasculature, it is exogenous administration increases the endothelium depende...

ea0049ep767 | Clinical case reports - Thyroid/Others | ECE2017

Polyglandular autoimmune syndrome type III-case report

Pancic Jelena Malinovic , Caric Bojana

The term polyglandular autoimmune syndrome (PAS) is used when there is a dysfunction of two or more endocrine glands associated with circulating antibodies directed at organspecific included glands. Neufeld and Blizzard classified PAS into two categories: type I and type II with the newly added category, type III, which does not include the adrenal cortex. PAS III includes several autoimmune diseases (autoimmune thyroiditis, immune-mediated diabetes mellitus, pernicious anemia...

ea0049ep768 | Clinical case reports - Thyroid/Others | ECE2017

Resistance of SIAD to tolvaptan despite initial control in progressive small cell lung cancer

Garrahy Aoife , Thompson Chris

A 58-year-old male was admitted through the emergency department with symptomatic severe euvolemic hyponatremia. Biochemistry was consistent with SIAD (plasma sodium (pNa) 107 mmol/l, plasma osmolality 230 mOsm/kg, urine sodium 36 mmol/l, urine osmolality (UOsm) 638 mOsm/kg, 0900 h plasma cortisol 484 nmol/l and thyroid function tests normal). Chest X-ray was normal but CT thorax confirmed a lung mass suspicious for malignancy. As the patient had symptoms of cerebral irritatio...

ea0049ep769 | Clinical case reports - Thyroid/Others | ECE2017

Overestimation of HbA1c by an unusual hemoglobin variant

Perez Fernando Garcia , Villanueva-Herraiz Sandra Isabel , Pena Jose Ignacio Fernandez , Benitez Ines Camacho , de Quiros Juan Manuel Garcia , de Pinillos Gordillo Guillermo Martinez , Ortiz Antonio Moro , Fernandez-Ladreda Mariana Tome , Leon Maria Victoria Cozar

Glycosylated haemoglobin (HbA1c) is considered the Gold Standard parameter for evaluating long-term glycemic control in individuals with Diabetes Mellitus (DM). The presence of hemoglobin variants or others conditions that modify its glycosylation, can affect the veracity of its measurement. The detection of these hemoglobinopathies and his knowledge by the clinicians is very important for the correct diagnosis and follow-up. We present the case of a patient who presented a he...

ea0049ep770 | Clinical case reports - Thyroid/Others | ECE2017

Myasthenia gravis associated with Graves’ disease and adrenal insufficiency

Elleuch Mouna , Elfekih Hamza , Hadjkacem Faten , Kalthoum Mahdi , Ammar Mouna , Rekik Nabila , Safi Wajdi , Mnif Mouna , Abid Mohamed

Introduction: Multiple autoimmune syndrome (MAS) is a rare condition, first described by Humbert and Dupond in 1988 and characterised by three or more autoimmune disorders in the same individual.Case description: Here we present a case of 14-year-old female patient diagnosed with ocular myasthenia gravis. The diagnosis of Graves’ disease was suspected on the basis of hyperthyroidism symptoms and confirmed by undetectable TSH level (<0.01 mUI/l) ...

ea0049ep771 | Clinical case reports - Thyroid/Others | ECE2017

Incidental asplenia in a patient with presumed type 2 autoimmune polyglandular syndrome (APS-2): misclassification or overlap?

Georgiou Thomas , Adamidou Fotini , Mintziori Gesthimani , Kita Marina

Introduction: Asplenia has been reported in 10% of patients with type 1 APS (APS-1), but has never been reported in APS-2. We describe a patient with presumed APS-2 and aplenia.Case report: A 69-year-old woman was diagnosed with B12 deficiency with severe anemia at age 21 and insulin dependent diabetes mellitus at age 33, following routine testing. At 59, she was hospitalized with salt wasting and a diagnosis of Addison’s disease was made, which was...

ea0049ep772 | Clinical case reports - Thyroid/Others | ECE2017

Immune checkpoint inhibitors related thyroiditis – a report of two cases

Donato Sara , Antunes Pedro , Simoes-Pereira Joana , Simoes Helder

Introduction: Immune checkpoint inhibitors (ICPIs) are recent approved drugs used in malignant melanoma, non-small-cell lung cancer and renal cell cancer. They act by activating host T cell against malignant antigens. Immune checkpoint blockade can lead to breaking of immune self-tolerance, thereby inducing autoimmune/autoinflammatory side effects, such as endocrinopathies. It may affect thyroid, adrenal and pituitary. We present two ICPIs induced thyroiditis cases.<p clas...

ea0049ep773 | Clinical case reports - Thyroid/Others | ECE2017

Nivolumab-associated pituitary, adrenal and thyroid autoimmune disorders

Bettencourt-Silva Rita , Oliveira Joana , Esteves Cesar , Hespanhol Venceslau , Fernandes Gabriela , Caeiro Claudia , Queiros Joana , Carvalho Davide

Background: Nivolumab is a monoclonal antibody specific for human PD-1 (programmed cell death protein-1), a checkpoint molecule highly expressed in several cancers. Nivolumab is an immunotherapeutic strategy for human cancer, but it can interfere with endocrine system.Case reports: We report four cases regarding nivolumab-associated endocrinopathies: (i) Male, 55-year-old, with previous normal cortisol and adrenocorticotropic hormone (ACTH) levels, treat...

ea0049ep774 | Clinical case reports - Thyroid/Others | ECE2017

Meigs’ syndrome in a 63 year-old woman – case report

Pascu Alina Mihaela , Hogea Mircea Daniel , Moga Marius Alexandru , Dima Lorena , Ifteni Petru Iulian , Gavris Claudia

Introduction: Meigs’ syndrome is defined as the presence of a benign ovarian tumour (fibroma), in association with ascites and hydrothorax. The characteristic feature of this condition is the resolution of the effusions once the tumour is surgically removed.Case report: A 63 year-old female patient was admitted to the Surgery Clinic with metroragia, abdominal distention, and a recent history of minor breath shortness. Pulmonary clinical examination ...