Searchable abstracts of presentations at key conferences in endocrinology
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19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

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20-23 May 2017, Lisbon, Portugal Further information

Guided Posters

Obesity

ea0049gp161 | Obesity | ECE2017

The association between olfaction and taste functions with serum ghrelin and leptin levels in obese women

Uygun Burcin , Kiyici Sinem , Ozmen Suay , Gul Zulfiye , Sigirli Deniz , Cavun Sinan

Aim: Olfaction and gustation have great importance on feeding behavior and food preferences. Recent published data suggests that olfaction and taste functions are modulated in response to changing levels of various molecules such as ghrelin and leptin which are play important roles on feeding and energy balance. We aimed to investigate the olfaction and taste functions in obese female patients and the association between serum ghrelin and leptin levels compared with healthy co...

ea0049gp162 | Obesity | ECE2017

Sarcopenic obesity and associated factors in older adults with diabetes: the 2009–2010 Korean National Health and Nutrition Examination Survey

Kim Jin Hwa , Ahn Hee Jung , Yang Tae Young , Kim Sang Yong

Objective: Sarcopenic obesity is a double burden for older people because it carries the cumulative risk of functional abnormality, metabolic, cardiovascular risk, and mortality compared to either sarcopenia or obesity alone. Diabetes is related to an increase in visceral adiposity and is associated with the risk of sarcopenia. The objective was to explore the association between sarcopenic obesity and diabetes and determine the associated factors with sarcopenic obesity in ol...

ea0049gp163 | Obesity | ECE2017

Resistance training reduces skeletal muscle inflammation even after 4-week detraining in obese rats

Seraphim Patricia , Freitas Marcelo , Teixeira Marcos , Teixeira Giovana , Nunes Maria Tereza , Filho Jose Carlos Camargo

The ingestion of high-fat diet has been considered a crucial factor in the genesis of subclinical systemic inflammation and insulin resistance. The resistance training (RTr) can be an effective tool for the prevention and treatment of immune-metabolic disorders through physiological and morphological adaptations. The purpose of the present study was to analyze the effects of RTr and cessation of training on muscle inflammation and expression of genes related to glucose metabol...

ea0049gp164 | Obesity | ECE2017

miR-26b is decreased in obesity and is associated with insulin resistance and visfatin levels

Nourbakhsh Mitra , Farahan Atieh Hosnieh , Yaghmaei Farideh , Moradgholi Saeedeh , Ahmadpour Fatemeh , Razzaghy-Azar Maryam

Obesity is one of the major causes of morbidity and mortality worldwide and is considered a risk factor for metabolic syndrome, type 2 diabetes and cardiovascular disease (CVD). miRNAs are epigenetic regulators of several aspects of metabolism and energy homeostasis and are involved in obesity and regulation of insulin sensitivity. miR 26b is among the obesity-related micoRNAs and is differentially expressed in preadipocytes and mature adipocytes in humans and is upregulated d...

ea0049gp165 | Obesity | ECE2017

The effect of FTO polymorphism rs 9939609 on obesity and metabolic disturbances in Polish people from Lower Silesia

Zdrojowy-Welna Aleksandra , Kolackov Katarzyna , Zatonska Katarzyna , Tupikowska-Marzec Malgorzata , Bolanowski Marek , Bednarek-Tupikowska Grazyna

Background: The association between fat mass and obesity-associated gene (FTO) polymorphism rs 9939609 and obesity was found in some European countries. However, the data concerning Polish population is insufficient. The relationship between FTO and metabolic disorders remains unclear.Methods: The study group consisted of 686 women and 418 men from Lower Silesia in Poland, aged 30–80 years (mean age 54.2±9.26 years). The examination included an...

ea0049gp166 | Obesity | ECE2017

Role of Elovl6 in brown and beige adipose tissue during β3-adrenergic receptor activation

Sharma Rahul , Matsuzaka Takashi , Hui Zao , Ohno Hiroshi , Takeuchi Yoshinori , Motomura kaori , Yahagi Naoya , Sekiya Motohiro , Nakagawa Yoshimi , Muratani Masafumi , Shimano Hitoshi

Anti-obesity therapeutics based on increasing the amount of brown fat have received more attention from industry as the biology and regulation of brown fat are better understood than that of beige fat. Cold exposure and treatment with β3 adrenergic receptor agonist are known to activate brown/beige adipose tissue. Many transcriptional pathways regulating brown/beige adipose tissue have been identified, the role of lipid biosynthetic enzymes in brown/beige adipose tissue h...

ea0049gp167 | Obesity | ECE2017

A link between sex hormones, obesity and gut microbiota

Martinez-Chacon Gabriela , Munukka Eveliina , Kumar Himanshu , Pietila Sami , Saarinen Niina , Toivonen Raine , Salminen Seppo , Hanninen Arno , Strauss Leena , Makela Sari

Sex steroids are involved in the development of obesity and metabolic disorders. The interrelationship between sex steroid balance and metabolism is complex, and the underlying mechanisms are still unclear. The impact of gut microbiota in development of obesity, inflammation and metabolic dysregulation has been suggested in humans and demonstrated in mouse models. Less is known about the interactions between sex steroids and gut microbiota. Based on available evidence, it is, ...

ea0049gp168 | Obesity | ECE2017

Effects of short sleep duration on energy metabolism and energy balance in subjects with overweight and obesity

Poggiogalle Eleonora , Donini Lorenzo , Gnessi Lucio , Mariani Stefania , Calabretto Marianna , Luisi Federica , Lenzi Andrea , Lubrano Carla

Introduction: The chronic reduction of sleep duration is associated to an increased risk of weight gain, but mechanistic aspects remain to be fully elucidated. The aim of our study was to examine the relationship between short sleep duration and energy metabolism, fuel selection and energy balance in overweight and obesity. Methods: Inclusion criteria were: age 18–65 years, BMI ≥25 kg/m2. Use of any CNS medications, any psychiatric disorders and night shi...

ea0049gp169 | Obesity | ECE2017

Blood mercury concentration in relation to overweight or obese among Korean children and adolescents: KNHANES 2009–2013

Park Kyung Hee , Kim Jeong-Hyeon

Background: Harmful effects of mercury on cardiovascular disease have been suggested in many epidemiologic studies. However, reports on harmful effect of mercury in relation to overweight or obesity have shown inconsistent findings.Methods: A total of 1577 children and adolescents (10–18 years of age) from the Korean National Health and Nutrition Examination Survey (KNHANES) 2009–2013. Overweight or obese group was defined as over the 85th perc...

ea0049gp170 | Obesity | ECE2017

Association of the FTO gene rs9939609 polymorphism with obesity in the Republic of Tatarstan

Khasanova Kamilya , Kiseleva Tatyana , Bogdanova Sabina , Valeeva Elena , Gubaidullina Svetlana , Ahmetov Ildus , Valeeva Farida

Aim: To investigate the possible association of the rs9939609 polymorphism in the FTO gene with obesity in the Republic of Tatarstan (RT).Materials and methods: The study involved 63 adult patients (21 men and 42 women; 38–77 years old) with overweight or obesity and 515 healthy young people (157 men and 358 women; 16–35 years old) with normal weight. We assessed clinical and biochemical parameters (blood lipid profile). The analysis of the rs9...

ea0049gp171 | Obesity | ECE2017

Effect of bariatric surgery on sexual function and sex hormone levels in obese patients: a meta-analysis

Wen Junping , Wen Lingying , Lin Wei , Li Liantao , Liang Jixing , Huang Huibin , Chen Gang

Objective: The aim of this meta-analysis is to evaluate the effect of bariatric surgery on sexual function and sex hormone levels in obese patients.Methods: Two independent investigators conducted a literature search of PubMed, Medline and Cochrane databases using the terms bariatric surgery, sexual function and sex hormone to identify appropriate human studies published in English about the effect of bariatric surgery on sexua...

ea0049gp172 | Obesity | ECE2017

Lipolytic effects of endogenous 3-iodothyronamine (T1AM) and synthetic analog SG-2 in vivo and in cultured adipocytes

Sabatini Martina , Rogowski Michael P , Alpergin Ebru S Selen , Assadi-Porter Fariba , Zucchi Riccardo , Chiellini Grazia

3-Iodothyronamine (T1AM) is a hormone like molecule structurally similar to TH, that has been reported to modulate energy metabolism by favoring lipid over glucose catabolism. To better understand the role played by T1AM on the regulation of lipid metabolism, in the present study we administered spontaneously obese mice with T1AM at two different dosages (10 and 25 mg/kg per day) for 7 days and the effects on body weight (BW) and lipid profiles were examined. In addition a flu...