Endocrine Abstracts (2017) 49 EP1402 | DOI: 10.1530/endoabs.49.EP1402

A rare case: papillary thyroid carcinoma in the ectopic thyroid

Yusuf Durmus1, Mehmet Celik2, Buket Yilmaz Bulbul2, Semra Ayturk2, Ebru Tastekin3, Nuray Can3, Atakan Sezer4, Funda Ustun5 & Sibel Guldiken2

1Trakya University, Medical Faculty, Department of Internal Medicine, Edirne, Turkey; 2Trakya University, Medical Faculty, Department of Endocrinology and Metabolism, Edirne, Turkey; 3Trakya University, Medical Faculty, Department of Pathology, Edirne, Turkey; 4Trakya University, Medical Faculty, Department of Surgery, Edirne, Turkey; 5Trakya University, Medical Faculty, Department of Nuclear Medicine, Edirne, Turkey.

Ectopic thyroid tissue is the localization of thyroid tissue at any place other than the normal localization of the thyroid during the migration of embryonic period. Concurrent normal thyroid tissue may accompany. It usually is seen in women and in the midline. Very rarely thyroid carcinoma can develop. Treatment is like normal thyroid carcinomas, suggesting simultaneous thyroidectomy if accompanied by normal thyroid tissue. A 42-year-old female patient presented with complaints of swelling on the right side of the neck for 3 months. There was no chronic disease or drug use in her story. On physical examination, a painless, moving 30×30 mm mass lesion was detected in the middle cervical region. Imaging revealed a mass lesion in the lower right cervical region near the right lobe of the thyroid gland, 36×25×35 mm heterogeneous signal density same as the thyroid gland. Histopathological examination of the excised mass revealed TTF1 positive, galectin positive, CK19 positive, HBME1 positive and 36×30 mm encapsulated follicular variant papillary carcinoma considered as thyroid carcinoma and lymphoid tissue has not been observed. Thyroid function tests and laboratory findings were normal. Thyroid ultrasonography revealed bilateral hypoechoic and isoechoic nodules maximal 1 cm in diameter and malignant lymphadenopathy 2 cm in the left cervical area. As a result of total thyroidectomy + neck dissection, 8 and 9 mm diameter papillary thyroid carcinoma encapsulated follicular variant was detected in the right lobe and thyroid carcinoma metastasis were observed in 3 of 10 lymph nodes removed in the left cervical area. This was evaluated as high-risk thyroid carcinoma and treated with radioactive iodine (RAI-131) at 150 mCi. At post-RAI whole body scan screening, 2 local foci were observed in the thyroid location and were followed up. The patient was followed for 6 months with asymptomatic levothione suppression therapy. We aimed to present a rare case of ectopic thyroid carcinoma.

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