Endocrine Abstracts (2017) 49 EP665 | DOI: 10.1530/endoabs.49.EP665

Decreased muscle strength is associated with vitamin D and albumin levels after bariatric surgery

Dilek Gogas Yavuz & Meliha Melin Uygur


Marmara University School of Medicine Section of Endocrinology and Metabolism, Istanbul, Turkey.


Bariatric surgery patients are at risk of decreasing in muscle mass, vitamin and protein deficiency. The aim of this study is to asses muscle strength, serum protein and vitamin levels after bariatric surgery.

Methods: 264 patients underwent bariatric surgery who completed 6 th month policlinic visits were included in the study. Patients were followed appropriately supplemented protein and vitamins as suggested; all study parameters were assessed before and after 3rd. mo. and 6th mo. of bariatric surgery. Handgrip dynamometry was used to measure static muscle strength. Serum Albumin, 25OH vitamin D (25OHD), Vitamin B12, ferritin and creatinine levels were measured by immune- chemiluminecanse method.

Results: Postoperatively, all patients showed a significant decrease in the BMI in 3 mo and 6 mo compared to preoperative levels (P:0.0001). Biochemical measurements are shown in Table 1. Serum ferritin and, creatinine levels were in reference range and not change during the follow-up. In a multivariate regression model showed that 25OH D and creatinine levels were independent risk factor for muscle strength (r2:16.2, P<0.0001). Serum albumin and handgrip measurements showed a positive correlation (r:0.23, P<0.001).

Table 1 BMI, handgrip and biochemical measurements before and after surgery in obese patients
Before surgery3rd mo. After surgery6th mo.fter surgeryP
BMI (kg/m2)48.3±8.940.4±7.938.1±110.0001
Handgrip (kg)28.1±9.221.6±7.521.3±6.40.001
25OHD (ng/dl)14.4±2025.6±15.731.9±490.0001
Vitamin B12 (ng/dl)284±154339±219326±2080.004
Albumine (mg/dl)4.42±0.24.30±0.34.07±0.90.0001

Conclusion: Although appropriate vitamin and protein supplementation bariatric surgery patients are at risk of decreased muscle strength related complications.

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