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Endocrine Abstracts (2017) 49 EP1385 | DOI: 10.1530/endoabs.49.EP1385

Ito Hospital, Tokyo, Japan.


Background: Papillary thyroid microcarcinoma (PTMC) has low malignant potential and an extremely good prognosis. However, surgical findings of asymptomatic PTC, can occasionally reveal tumor invasion into the recurrent laryngeal nerve (RLN). The present study assessed the feasibility of evaluating tumor invasion into the RLN using ultrasonography (US) and computed tomography(CT).

Materials and methods: Of 7,916 patients with a PTC who underwent surgery at our hospital, 35 with preoperative tumors that were ≤10 mm, without distal metastasis or lymph node metastasis, and with surgical findings of RLN invasion were included. The location of the tumor and the degree of contact with the thyroid capsule (DCTC) were examined by US and CT.

Results: Ten of the 35 patients were treated by combined resection of the RLN, and 25 patients were treated by shaving the RLN. US revealed that the tumor was located at the dorsal side of the thyroid in 31 patients (88.5%). In all patients who were treated by combined resection of the RLN, the tumor was located at the dorsal side of the thyroid. Among these patients, the DCTC determined by US was ≥25% in nine patients and <25% in one. Among those who were treated by RLN shaving, the DCTC was ≥25 and <25% in nine and 16 patients, respectively (P=0.003). The DCTC was ≥25% in all patients who were treated combined resection and in 15 of the 25 patients who treated by RLN shaving (≥=0.018) according to CT imaging. The tumor was located 1–1.5 cm from the cricoid cartilage in most patients who were treated by combined resection.

Conclusions: When a PTC is located at the dorsal side of the thyroid with ≥25% DCTC, surgery should be selected for RLN invasion. Our results showed that the accuracy of predicting recurrent laryngeal nerve invasion can be improved by combining US with neck CT.

Volume 49

19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

European Society of Endocrinology 

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