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Endocrine Abstracts (2017) 49 EP189 | DOI: 10.1530/endoabs.49.EP189


The Department of Endocrinology and Diabetology of Hedi Chaker Hospital in Sfax, Sfax, Tunisia.

Introduction: Neuroendocrine tumors may develop in almost any organ. These types of tumors may present with giant and asymptomatic mass. We describe a case of a large non functional neuroendocrine tumor reported in the department of endocrinology and diabetology of Hedi Chaker hospital in Sfax-Tunisia in 2016.

Presentation of case: A 28 years old male presented with asthenia, gastric heaviness and epigastric pain. Further computerized tomography, a large mass (20 cm) near the stomach in the coeliomesenteric region has been demonstrated. Magnetic Resonance Imaging has showed the presence of a voluminous encapsulated mass with abundant vascularization and central necroses, measuring 18.5 cm×14.5 cm compressing the vascular structures. The dosage of methoxylated plasma derivatives was negative. The dosage of NSE was returned positive at 30.5 ng/l. The biopsy of the mass showed a histological and immunohistochemical aspect of a neuroendocrine tumor. The therapeutic decision was to start with exploratory laparotomy and tumor excision if possible. Because of the vascularized character and significant bleeding during the intervention, a surgical abstention was decided. The patient had two chemoembolization sessions with good tumor response. It is being evaluated for possible re-intervention.

Conclusion: The incidence of neuroendocrine tumors has been increasing during the last decade, underscoring the need to improve our understanding of their biology and behavior especially.

Volume 49

19th European Congress of Endocrinology

Lisbon, Portugal
20 May 2017 - 23 May 2017

European Society of Endocrinology 

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