ECE2017 Eposter Presentations: Diabetes, Obesity and Metabolism Obesity (81 abstracts)
Relation of insulin resistance to neurocognitive function and electroencephalography in obese chıldren
Onur Akın , İbrahim Eker , Mutluay Arslan , Süleyman Tolga Yavuz , Sevil Akman , Mehmet Emre Taşçılar & Bülent Ünay
Gülhane Education and Research Hospital, Ankara, Turkey.
Background: This study aimed to investigate neurocognitive functions and electroencephalography (EEG) parameters in normoglycemic obese children.
Method: A total of 73 obese children (38 male and 35 female) and 42 healthy children (21 male and 21 female) were recruited. Biochemical disturbances and insulin resistance (IR) were investigated. The Wechsler Intelligence Scale for Children-Revised (WISC-R) and EEG were performed for all children. Obese participants were classified according to the presence of IR. Data were compared between these subgroups.
Results: Verbal scores on the WISC-R of the IR+ Group were significantly lower than the control group and the IR– Group. There were no differences between groups with respect to other parameters of the WISC-R and EEG. Verbal and total scores of the WISC-R were negatively correlated with HOMA-IR values. In the EEG study, slowing during hyperventilation was seen significantly more frequently in obese children than non-obese children.
Conclusion: Neurocognitive functions, particularly verbal abilities, were impaired in obese children with IR. On the other hand, EEG results did not differ in terms of obesity and IR. IR may be associated with neurocognitive abnormalities in obese children.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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