Diabetes (to include epidemiology, pathophysiology)

ea0056p331 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Evaluation of community pharmacy-based services for type-2 diabetes in an Albanian setting: pharmacist survey

Background: Diabetes type II is an emerging chronic disease in developing countries. Currently the management of diabetes in developing countries is mainly hospital or clinic based. With burgeoning numbers of patients with diabetes, other models need to be evaluated for service delivery in developing countries. Community pharmacists are an important option for provision of diabetes care. Currently, data regarding practices of community pharmacists in diabetes care in Albania a...

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ea0056p332 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Estimation of HbA1c in hospitalized patients with bronchial asthma

Qasim Bayar , Haj Safer , Ahmed Herish

Background: Asthma is a chronic inflammatory respiratory disease. Stress hormones may increase in asthma and expected to induce hyperglycemia. Some anti-asthma medications increase blood glucose levels e.g. Beta-agonist, while others are known hyperglycemic agents e.g. steroids. People who have experienced stress hyperglycemia during severe illness have a threefold risk of developing diabetes in subsequent years, and it may be appropriate to screen for diabetes in surviv...

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ea0056p333 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Inpatient diabetes management service, 30-day readmissions and length of stayof patients with diabetes

Mandel Samantha , Mathioudakis Nestoras , Golden Sherita Hill , Zilbermint Mihail

Context: Diabetes mellitus (DM) is common among hospitalized patents. An inpatient diabetes management service (IDMS) has been implemented to provide better glycemic control. The impact on length of stay (LOS) and 30-day readmission rates is unknown.Objective: We retrospectively analyzed LOS and 30-day readmission rate of patients with known DM admitted to a 240-bed community hospital in suburban Maryland between January 2016 and May 2017.<p class="a...

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ea0056p334 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Evolution of the degree of glycemic control in a cohort of patients with type 2 diabetes mellitus. study to 26 weeks

Herranz-Antolin Sandra , Alvarez-de Frutos Visitacion , Torralba Miguel

Objective: To evaluate the evolution of glycemic control in a cohort of patients with type 2 diabetes mellitus (T2DM) after its assessment in endocrinology.Methods: Prospective cohort study. 465 patients with T2DM who were not followed up at an endocrinology clinic were included. This study was approved by the Ethics and Clinical Research Committee of the University Hospital of Guadalajara.Results: Mean age was 63.4±12.5 years...

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ea0056p335 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Study of the association of transcription factor 7 like 2 gene polymorphism with type 2 diabetes mellitus and diabetic nephropathy in the Egyptian population

Alnaggar Alshaimaa Rezk , El-salam Randa Fayez Abd , Rady Normeen Hany , Ishak Marianne Fathy , Ammar Soha Hamed

Background: Studies from different parts of the world have given controversial results regarding the association of transcription factor 7like 2 (TCF7L2) gene polymorphism with Type 2 diabetes mellitus (T2DM) and diabetic nephropathy (DN). Aim: This study aimed to investigate if TCF7L2 gene polymorphism, rs12255372(G>T) is a risk factor for the development of T2DM and DN in type 2 Egyptian diabetic patients. PATIENTS AND METHODS: This study was conducted ...

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ea0056p336 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Relationship between serum zinc, glycemic status and HOMA2 parameters in a regional Australian hospital population

Lim Sarah , Milton Abul Hasnat , Iyengar Vasudha , Islam Md Rafiqul

Aim: Previous studies demonstrated lower serum zinc among prediabetics and diabetics, compared to normoglycaemics. There is no current epidemiological data available in regional Australia examining the association between serum zinc and glycaemic status. This study was conducted to determine the relationship between serum zinc, glycaemic status and Homeostasis Model Assessment (HOMA-2) parameters in a regional Australian hospital population.Methods: A re...

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ea0056p337 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

The role of polysomnography for detection of OSA in patients with type 2 diabetes in the Uzbek population

Muminova Sitorakhon , Daminova Lola , Esimova Dina

Actuality: According to the International Classification of Sleep Disorders in type 2 diabetes, the risk of obstructive sleep apnea (OSA) in middle-aged people ranges from 18% to 36%. In a report by S. D. West et al. the incidence of sleep apnea in patients with diabetes is estimated at 23% compared with 6% in the general population. In a recent study, AS Peltier et al. it was found that 79.2% of patients with OSA had a violation of glucose tolerance and 25% were first diagnos...

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ea0056p338 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Transcription Factor 7 Like2 Gene Polymorphisms and Susceptibility to Type 2 Diabetes Mellitus in a cohort of Egyptian diabetic patients, a pilot study

Mandour Iman , Darwish Rania , Salam Randa , Naguib Merva , El-Sayegh Sarah

Purpose: Transcription factor 7-like 2 (TCF7L2) variants are known risk factors of type 2 diabetes (T2DM).However; this association is not consistent among different populations. The current study aimed at investigating the relationship between rs 7903146, rs 12255372 variants of TCF7L2 and susceptibility to T2DM.Patients and methods: This case control study included 60 diabetic patients and 60 matched unrelated healthy controls. Genoty...

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ea0056p339 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Undiagnosed diabetes and related risk factors in postmenopausal women: the 2011–2012 Korean National Health and Nutrition Examination Survey

Kim Sang-Yong , Kim Jin-Hwa

Aims: Postmenopause is associated with unfavorable metabolic disturbances and might be related to increase the risk of diabetes. Identification of undiagnosed diabetes and at-risk individuals may allow to initiate earlier management and to prevent diabetic complication. The objective of the present study was to determine the prevalence of undiagnosed diabetes and related risk factors in postmenopausal women.Methods: This study was based on data from the ...

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ea0056p340 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Comparison of quality of life and symptoms of depression in diabetes combined with gastroparesis and without it

Orlova Marina , Frolova Arina , Rodionova Tatiana

Objective: To assess the quality of life, the presence and severity of depressive symptoms in patients with diabetes combined with gastroparesis and without itMethods: Forty three patients with diabetes were included in the study. The presence and severity of gastrointestinal symptoms, as well as the intensity and frequency of symptoms over the last 2 weeks, were measured with the Patient Assessment of the upper gastrointestinal symptom severity index (P...

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ea0056p341 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Predictors of anxiety development at diabetes mellitus type 1

Navmenova Yana , Savasteeva Irina , Makhlina Elena , Mokhort Tatiana

Objective: To assess possible predictors of anxiety disorder development at Diabetes Mellitus type 1.Materials and methods: There were examined 164 patients (93 males and 71 females) with diabetes mellitus type 1 (DM) at the age from 18 to 60 years old. The level of anxiety was assessed with the use of the Hospital Anxiety and Depression Scale (HADS), blood glucose level was determined in the fasted state and 2 hours after the meal. Also there was monito...

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ea0056p342 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Comparative analysis of the prevalence of type 2 diabetes according to the screening and register data in Uzbekistan

Ibragimova Nilufar , Tregulova Raisa , Normatova Nargiza , Djalalov Sherzod

Purpose of the study: To carry out the comparative analysis of the prevalence of Type 2 Diabetes (T2DM) according to the screening and register data in Uzbekistan.Material and methods: Within the framework of WDF international project Prevention of diabetes in rural population of Uzbekistan, with the support of the Ministry of Health of the Republic of Uzbekistan, the screening campaign was conducted in 6 rural regions to actively identify di...

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ea0056p343 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Nutrition of non-fasting patients with diabetes during the month of Ramadan

Lassoued Najoua , Abid Neila , HadjKacem Faten , Charfi Nadia , Abid Mohamed

Introduction: Fasting during the month of Ramadan is the most observed religious practice by Muslims. Diabetes is one of the condition that exempt Muslims from fasting because of the risk of complications. The International Diabetes Federation states that high-risk patients should not fast. The objective of this study was therefore to evaluate the daily food intake during the month of Ramadan in non-fasting patients with diabetes in order to detect diet mistakes ma...

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ea0056p344 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Evaluation of procalcitonin levels in diabetic and diabetic nephropathic patients

Dagdeviren Murat , Beyan Esin , Dagdeviren Tanyel Sema , Copuroglu Esra , Cagir Yavuz , Dogan Ozlem , Ertugrul Derun Taner , Altay Mustafa

Aim: To determine how serum procalcitonin (PCT) levels are affected in diabetic and diabetic nephropathic patients, it is important to determine whether PCT is indicative of an inflammation in these patients.Materials and methods: The study included 175 patients (75 diabetic nephropathy (group 1), 75 diabetic (group 2) and 25 non-diabetic nephropathy (group 3)) and 75 healthy volunteers. Serum and urine creatinine, serum high sensitive C- reactive protei...

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ea0056p345 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Telmisartan increases gluconeogenesis by inducing PKCζ-Thr⁴¹⁰ phosphorylation in hyperglycemia-treated HepG2 cells and high-fat diet-fed mouse liver

Cho Du-Hyong , Cho Kae Won , Song Kee-Ho

Telmisartan, an angiotensin II type 1 receptor blocker (ARB), is widely prescribed for the treatment of hypertensive patients with simultaneous diabetes mellitus (DM). Unlike other ARBs, telmisartan is reported to have various ancillary effects as well as common blood pressure-lowering effect. In this regard, telmisartan improves endothelial dysfunction and cardiovascular complications in DM patients and is recently reported to reduce new-onset DM incidence. However, effects a...

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ea0056p346 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Diabetes complications and comorbidities in patients newly diagnosed with diabetes in newfoundland and labrador (NL): gender differences

Parihar Richa , Asghari Shabnam

Introduction: Diabetic patients are known to develop complications and co-morbidities as a result of the disease. Determining gender susceptibility to diabetic complications can lead to improved patient-centered care for patients.Objectives: To examine the gender differences on complications and comorbidities in patients newly diagnosed with diabetes in NL.Methods: A retrospective cohort study, patients were followed for 5 years fr...

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ea0056p347 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Visfatin concentration and anthropometric/biochemical parameters in healthy individuals-preliminary study

Nowak Justyna , Kulik-Kupka Karolina , Kowalska Joanna , Zielen-Zynek Iwona , Hudzik Bartosz , Zyla Anna , Stanuch Beata , Zubelewicz-Szkodzinska Barbara

Visfatin (pre-B cell colonyenhancing factor) is a adipocytokine playing an important role in glucose homeostasis. High concentrations of visfatin are observed in obese people. Previous studies suggest that estimation of visfatin concentration could be a promising tool for predicting obesity or its metabolic consequences. The aim of the study was to evaluate the correlation between visfatin concentration, selected anthropometric parameters (BMI, WHR, BAI, VAI index) and biochem...

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ea0056p348 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Serum soluble vascular adhesion molecules and highly sensitive C: reactive protein in elderly type 2 diabetic patients with mild cognitive impairment

Hosny Salwa , Bekhet Meram , Khater Mohamed , bahaaeldin Ahmed , Hasanin Ghada

Background: T2DM is a metabolic disorder characterized by high blood glucose in the context of insulin resistance and relative insulin deficiency with disturbances of carbohydrate, fat, and protein metabolism.T2DM is a risk factor for Alzheimers disease and mild cognitive impairment. The etiology of cognitive impairment in people with T2DM is uncertain, but it is most likely multi factorial. Chronic hyperglycemia, cerebral micro vascular disease, severe hypoglycemia, and...

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ea0056p349 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Evaluating quality of diabetic care in patients with severe mental illness (SMI) in an academic primary care clinic

Katkar Rujuta , Gudleski Gregory , Bakhai Smita

Background: Higher prevalence of type 2 Diabetes Mellitus (DM II) has been reported in patients with SMI (serious mental illness). SMI patients get suboptimal diabetes care as compare to non- SMI patients.Methods: We tested the hypothesis that SMI patients get suboptimal diabetes care as compare to non- SMI patients. We did a retrospective cohort study in an academic, primary care clinic for underserved,urban population.SMI patients included schizophreni...

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ea0056p350 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Prorenin and secreted frizzled-related protein-4 levels in women with gestational diabetes mellitus

Ipekci Suleyman , Baldane Suleyman , Kebapcilar Ayse Gul , Abusoglu Sedat , Beyhekim Hasan , Ilhan Tolgay Tuyan , Unlu Ali , Kebapcilar Levent

Background: This study was designed to investigate prorenin and secreted frizzled-related protein-4 (SFRP-4) levels in pregnancies with or without gestational diabetes mellitus (GDM).Materials and methods: A total of 76 pregnant women were included in the study. Thirty-five of the pregnant women were included in the GDM group according to the results of oral glucose tolerance tests (OGTT) and 41 pregnant women were included in the control group.<p cl...

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ea0056p351 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Novel inflammatory pathways in monocytes of type 2 diabetes patients are modulated by vitamin D

Nejatian Nojan , Penna-Martinez Marissa , Badenhoop Klaus

Type 2 diabetes (T2D) patients have a high cardiovascular risk due to vascular inflammation and dyslipidaemia. Furthermore vitamin D (VD) deficiency is highly prevalent. Our aim was to elucidate the role of fatty acid receptors in inflammatory pathways and their regulation by VD. We therefore examined the VD effect on gene expression of Arachidonate 5-lipoxygenase (ALOX-5) and Sphingosine-1-phospate receptors (S1PR1 and S1PR2) in primary isolated monocytes of T2D patients and ...

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ea0056p352 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Serum adiponectin in male type 2 diabetic patients exposed to ionizing radiation in early years

Dombrovska Natalia , Kaminskyi Oleksii , Afanasyev Dmitryi , Pleskach Oksana , Bazyka Dmitryi

Prevalence of diabetes mellitus in the world is constantly increasing and today the type 2 diabetes pandemic is the point of issue. The type 2 diabetes incidence in exposed individuals i.e. the participants of the Chernobyl Nuclear Power Plant accident consequences clean-up works (ChNPP ACUW) in Ukraine in the post-accident years was about 15-21%, which was significantly higher (p<0.0001) than in the non-irradiated persons (3-9%). The adipose tissue is actively in...

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ea0056p353 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Decreased spexin levels in patients with type 1 diabetes

Karaca Anara , Bakar Filiz , Ersoz Gulcelik Nese

Spexin is a novel peptide which has a potential role as a biomarker of insulin resistance, diabetes and obesity. We aimed to investigate spexin levels in lean type 1 diabetes patients and spexins role on glycemic parameters without the presence of obesity or insulin resistance.Patients and methods: This cross-sectional study included 29 type 1 diabetic patients and a control group of 23 healthy subjects adjusted for age, sex and body mass index (BM...

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ea0056p354 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Increase in C-peptide levels after short term glycemic control in patients with type 2 diabetes mellitus: myths or facts?

Topaloglu Omercan , Evren Bahri , Sahin Ibrahim

Introduction: Long term control of glucotoxicity has been shown to increase the secretion of insulin and C-peptide (Cp) from beta cells. However, there is limited data concerning the effect of short term glycemic control and reversal of glucotoxicity on basal Cp. We aimed to investigate the change in serum Cp levels after short term glycemic control in patients with uncontrolled type 2 diabetes mellitus (DM).Materials and methods: A total of 123 patients...

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ea0056p355 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Incidence of glucocorticoid-induced hyperglycemia among hospitalized nondiabetic patients

Nakhleh Afif , Shehadeh Naim , Hochberg Irit

Introduction: High-dose glucocorticoid therapy is a recognized cause of hyperglycemia. Given the paucity of literature regarding the incidence of glucocorticoid-induced hyperglycemia among nondiabetic patients, we commenced this study in order to assess its incidence and to identify risk factors.Design: A retrospective longitudinal cohort study.Methods: We retrieved patients over 18 years old, without prior diabetes diagnosis or tr...

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ea0056p356 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Diabetes after liver transplantation

Moreno-Moreno Paloma , Barrera-Martin Ana , Munoz-Jimenez Concepcion , Rosa Alhambra-Exposito Maria , Angeles Galvez-Moreno Maria

Objective: Diagnosis of diabetes after transplantation (NODAT) has been described in up to 25% of cases. NODAT is a metabolically complex disorder, similar to type 2 diabetes. Factors that influence the development of NODAT are: BMI, HCV and immunosuppression. Objective: to know the prevalence and incidence of diabetes mellitus (DM) in liver transplant patients of our hospital.Patients and methods: Retrospective descriptive study of liver transplant pati...

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ea0056p357 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Distribution of Korean obese patients based on National Health Insurance Claim Data in 2016

Kang Ryungwoo , Lee YounSue , Chee Deborah

South Korea has a universal health coverage system that the National Health Insurance covers approximately 98% of the overall Korean population. The claims data of HIRA contains 46 million patients per year that account for 90% of the total population in Korea and include claims from almost 80,000 healthcare service providers across South Korea as of 2011. National Health Insurance (NHI) reimbursement coverage continues to expand and there will be full reimbursement of cancer,...

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ea0056p358 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Think insulin: a prospective study of the knowledge of insulin preparations and administration in a Cohort of nurses in district general hospital

Jade Shepherd Emma , Ashotush Surya , Jones Sian , Jones Julie , Mumford Beth , Harrison Gaynor , Abusahmin Hussam

Introduction: Blood glucose control in insulin-dependent diabetes is heavily influenced by compliance, and how insulin is administered, which is emphasised to those with diabetes. However, when a patient is admitted to hospital, the administration of insulin is often by a nurse. The aim of this study was therefore to assess the knowledge of nurses around this subject, and to identify if there was a need for further training.Method: We conducted a prospec...

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ea0056p359 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Association between NK cell activity and glucose regulation in type 2 diabetes patients

Hye Kim Jung , Park Kahui , Bae Lee Sang , Sun Nam Ji , Kang Shinae , Suk Park Jong , Woo Ahn Chul , Kim Yu-Sik

Introduction: NK cells are cytotoxic lymphocytes critical to innate immunity. The purpose of this study is to find out the difference in NK cell activity between type 2 diabetes patients and controls, and to investigate the association between NK cell activity and glucose control.Methods: Forty-nine subjects were enrolled in this study, with 23 type 2 diabetes patients and 26 normal glucose tolerant controls. Anthropometric and biochemical parameters wer...

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ea0056p360 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

The effects of Korean red ginseng on diabetic complications and glucose modulation in type 2 diabetic patients

Woo Ahn Chul , Hye Kim Jung , Park Kahui , Bae Lee Sang , Sun Nam Ji , Kang Shinae , Suk Park Jong , Kim Yu-Sik

Background: Korean red ginseng (KRG) has been shown to improve glucose tolerance and insulin resistance in several human studies. However, human studies on the effects of KRG on diabetic complications are lacking. We performed this study to investigate the effects of KRG administration on glucose metabolism and chronic diabetic complications in type 2 diabetes patients.Methods: This study was a randomized, double-blind, placebo-controlled trial. 83 type ...

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ea0056p361 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Phenotypic and autoimmunity analysis of patients with type 1 diabetes mellitus onset

Maria Diaz Perdigones Cristina , Hern Carmen , Damas Fuentes Miguel , Jose Picon Cesar Maria , Luis Pinzon Martin Jose , Molina Vega Maria , Tinahones Madueno Francisco

Introduction: Type 1 diabetes mellitus (T1DM) is considered, in general, a disease of children and young adults with normal body mass index (BMI), linked to a genetic susceptibility based on autoimmunity. However, we know that it can be diagnosed at any age and we must differentiate it from type 2 diabetes mellitus.Objetives: To investigate the phenotypic characteristics and the presence of specific autoimmunity in T1DM patients diagnosed in our hospital...

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ea0056p362 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Is it useful the O’Sullivan test ≥200 to diagnose gestational diabetes mellitus (GDM)?

Molina-Vega Maria , Picon-Cesar Maria Jose , Hernandez-Garcia Carmen , Damas-Fuentes Miguel , Diaz-Perdigones Cristina , Tinahones-Madueno Francisco

Introduction: A two-step approach is usually used to diagnose GDM. At 2428 weeks of pregnancy, a 50 g 1-hour glucose or OSullivan test is performed. If it is positive (≥140 mg/dl), it is followed by a 100 g-3 hours-Oral Glucose Tolerance Test (OGTT) which is considered positive if at least two or more values are ≥ of reference values (105-190-165-145 mg/dl). Despite it is not include in any clinical practice guideline, sometimes the 100 g OGTT is obviat...

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ea0056p363 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Study on sphingolipids in tissues of animals with the diet-induced obesity

Saatov Talat , Zainutdinov Bakhodyr , Irgasheva Sanobar , Mustafakulov Mukhammadjon , Ishankhodjaev Tokhir , Ibragimova Elvira

Disturbance in insulin signaling under effect of sphingolipids is thought to be the mechanism underlying the obesity-mediated insulin resistance. The work was initiated to study sphingolipid metabolism in tissues of rats with obesity induced by a prolonged high-calorie diet. The lipid extraction and purification was performed by Folchs method; concentrations of sphingosine and ceramide were measured by Lauter et al. method. In obesity, the levels of total gangli...

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ea0056p364 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Influence of HLA pattern on the age at onset of type 1 diabetes mellitus

Fernandez Pedro Gonzalez , Rubio Elsa Fernandez , Etxebarria Ines Urrutia , Frutos Teba Gonzalez , Machado Natalia Maruri , Gonzalez Luis Castano , Saenz Sonia Gaztambide

Aim: To determine, in type 1 diabetes mellitus (T1DM) patients, if there is any relationship between the age at onset and the number of HLA risk alleles for T1DM (DRB1*03 and DRB1*04).Methods: Retrospective study. We selected patients with T1DM diagnosis (pancreatic autoimmunity and insulin-dependent diabetes) and age at onset >15 years, identifying 275 subjects (59.6% men and 40.4% women), with a median age at onset of 31 years (interquartile range ...

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ea0056p365 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Lipoatrophic Diabetes Mellitus: a rare special type!

Fathy Shaimaa A , Seif Aasem , Sherif Heba , Farouk Dina

Introduction: Lipodystrophic syndromes are a heterogeneous group of congenital or acquired disorders characterized by either complete or partial lack of adipose tissue. Other prominent abnormalities of these disorders include Diabetes Mellitus and acanthosis nigricans due to the associated insulin resistance. Liver affection is common due to fatty infiltration of the liver, which can lead to cirrhosis and its complications.Clinical case: A 31 years old s...

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ea0056p366 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Does gender-affirming hormone therapy alter insulin resistance in transgender persons?

Abosi-Appeadu Kessewa , Maertelaere Anne-Sophie De , Shadid Samyah , Defreyne Justine , T'Sjoen Guy

Background: Gender-affirming hormone therapy in transgender persons induces secondary characteristics of the experienced gender. However, androgens and estrogens are also thought to be involved in insulin sensitivity and research suggests a dose-dependent risk for developing insulin resistance when administrated in supraphysiological doses.Aims: To assess the influence of gender-affirming hormone therapy on glucose metabolism in transg...

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ea0056p367 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Diagnosis and optimal medical management of patients with maternally inherited diabetes and deafness (MIDD)

Ng Nicholas , Sanchez Begonia , McCarrick CJ , Mangan Cian , Byrne Maria

Background: Maternally inherited diabetes and deafness (MIDD) is a rare disease affecting approximately 1% of all diabetics. The most common mutation involved is a single base mutation (A-G) at position 3243 within the tRNALEU(UUR) gene. The clinical characteristics normally associated with this disease include sensorineural hearing loss, macular pattern dystrophy, cardiomyopathy, and diabetes. This study aims to identify clinical phenotype and insulin secretory res...

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ea0056p368 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Predictors of non-alcoholic fatty liver disease in metabolic syndrome

Savasteeva Irina , Rozhko Alexander , Selkina Veronica , Navmenova Yana , Rusalenko Maria

The results of a survey of 209 patients with Diabetes mellitus type 2 (DM 2) and 94 patients with X-syndrome were analyzed. Non-alcoholic fatty liver disease (NAFLD) is verified in 91.9% of cases with DM 2 and 83.0% with X-syndrome. Predictors that significantly influenced the development of NAFLD in X-syndrome have been identified: age (b=0.07; Exp (b)=1.07(1.02÷1.14); P<0.02); body mass index (b=0.37, Exp(b)=1.45 (1.16÷1.81), P<0.001), tot...

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ea0056p369 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Carbohydrate metabolism indicators in athletes who stopped using anabolic androgenic steroids

Lykhonosov Mykola

Introduction: The use of steroids for the formation of a sports figure is widespread. Anabolic androgenic steroids (AAS) are used in large doses than in therapeutic practice. Studies of the side effects of AAS on carbohydrate metabolism are hampered due to the self-over-the-counter use of AAS.Hypothesis: We hypothesized that with the abolition of AAS, the effect of elevated doses of testosterone (Ts) and nandrolone (ND) decanoate on the utilization of gl...

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ea0056p370 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Carbohydrate metabolism disorders in patients with Graves treated with systemic corticosteroid regimen

Rutkowska Joanna , Bandurska-Stankiewicz Elzbieta , Myszka-Podgorska Katarzyna , Matuszewski Wojciech , Szychlinska Magdalena , Stefanowicz-Rutkowska Magdalena

In patients with Graves disease and Graves orbitopathy (GO), the diagnosis was based on clinical activity score (CAS), TSH-receptor antibodies, orbital MRI assesment. Thyreometabolic status was assessed by TSH, FT4, FT3. Before the administration of high-dose intravenous glucocorticoids oral glucose tolerance test (OGTT) was performed obligatory. The patient with confirmed diabetes were excluded form the study. Acute hyperglycaemia was diagnosed at the glucose concentrat...

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ea0056p371 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

A difficult synchronous diagnosis; Type 2 Diabetes and insulinoma

Sefa Bakiner Okan , Bozkirli Emre , Haydardedeoglu Filiz Eksi , Bagir Gulay Simsek , Ertorer Melek Eda

Background: In the literature there are rare cases of patients with known Type 2 Diabetes Mellitus whom are diagnosed as insulinoma. However a synchronous diagnosis with insulinoma and diabetes for a patient presenting with hypoglycemia symptoms is not an expected condition.Case: A 79 years-old female patient was sent to our Endocrinology outpatient clinic because of repeating minor and major hypoglycemia attacks. She had no important finding in her back...

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ea0056p372 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Immunoglobulin G4 related pancreatitis; can it be a rare cause of secondary diabetes?

Bozkirli Emre , Bakiner Okan Sefa , Bagir Gulay Simsek , Haydardedeoglu Filiz Eksi , Ertorer Melek Eda

Background: Autoimmune pancreatitis (AIP) is a relatively new entity in which the exocrine pancreas shows lymphocytic infiltration. There are two subtypes of AIP; Type 1 related with Immunoglobulin G4 (IgG4) as the pancreatic manifestation of IgG4-related disease (IgG4-RD), and Type 2 related with granulocytic infiltration. The characteristic features of Type 1 AIP are increased serum IgG4 levels, lymphoplasmacytic sclerosing pancreatitis (infiltration of IgG4+ plasmacytes and...

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ea0056p373 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Evaluation of glycemia correction during sleeping on the somnological indicators in type 1 diabetes patients

Darashkevich Ina , Mokhort Tatiana , Nikanava Lola , Tishkovsky Serhey

Fluctuations of glycemia, the rate of glycemia decreasing, the chronic decompensation type 1 diabetes adversely influenceon diabetic complications development. Increased glycemia during sleep leads to a change in the structure of sleep and a decrease in its functions.The aim of the study was to assess the effect of glycemic values and its correction during sleep on somnological indicators.Materials and methods: The study incl...

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ea0056p374 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Insulin resistance and β-cell function in patients with cystic fibrosis

Roman Angel Rebollo , Moreno Paloma Moreno , Martin Ana Barrera , Exposito Maria Rosa Alhambra , Laguna Maria Dolores Alcantara , Barrios Jose Manuel Vaquero , Continente Alfonso Calanas , Moreno Maria Angeles Galvez

Introduction: Recent studies defend the measurements of insulin resistance and β-cell function to assess the endocrine pancreatic function in patients with cystic fibrosis (CF). HOMA-IR indexes greater than 1 translate insulin resistance and HOMA-%β values lower than 100% imply an altered β-cell function.Aim: To describe insulin resistance and β-cell function using HOMA-IR and HOMA-%β indexes in patients with CF and compare them ...

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ea0056p375 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

HNF-1β maturity-onset diabetes of the young (MODY 5): defining diabetes etiology in a family with different diabetes phenotypes

Silva Carlos , Garcia Elena , Villa Gema , Males David , Romero Juan Carlos , Martinez Guillermo , Leon Miguel

Introduction: HNF-1β maturity-onset diabetes of the young (MODY5) is uncommon, nevertheless accurate diagnosis guides individualized management and informs prognosis in probands and relatives.Objective: To emphasize the importance of the appropriate use of clinical, biochemical and genetic investigations for the correct classification of diabetes etiology.Case-report: A 35-year-old overweight Latin-American male was diagnosed ...

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ea0056p376 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Habitual dietary intake in response to futsal-based exercise in people with type 1 diabetes

Cosma Daniel Tudor , Silaghi Cristina Alina , Silaghi Horatiu , Georgescu Carmen Emanuela , Veresiu Ioan Andrei , Campbell Matthew D

Background: Adequate and appropriate nutrition in type 1 diabetic athletes is essential not only to increase the physical performance but also to prevent the hypoglycemic events. Detailed nutrition history represents the initial step in developing a proper meal plan according to the specific characteristics of the physical activity performed.Purpose: This study assessed changes in habitual dietary intake and macronutrient distribution in response to inte...

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ea0056p377 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

TWEAK levels in patients with prediabetes and diabetes mellitus

Okuturlar Yildiz , Kocoglu Hakan , Serin Sibel Ocak , Ercan Tarik , Hursitoglu Mehmet , Mert Meral , Ozdemir Bahar , Erismis Betul , Gedikbasi Asuman , Harmankaya Ozlem

Introduction: Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) belongs to TNF family and is released from inflammatory cells. It has been reported that TWEAK has several biological actions ranging from cell proliferation to stimulation of apoptosis. In in vitro studies, it was reported that TWEAK has alleviating effect on insulin resistance in hepatocytes. TWEAK decreases insulin resistance induced by TNF-a through activation of phosphatase 2A pathway in a...

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ea0056p378 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Description of clinical, biochemical and radiological variability of Hepatocyte Nuclear Factor-1βeta (HNF1β) Mutations

Zamuner Matilde Bettina Mijares , Ng Nicholas Khay Jin , Siddique Nadia , Burke Marie , Byrne Maria

Background: HNF1β mutations are one of the commonly identified genetic causes of renal malformations, but one of the less common forms of MODY. HNF1β is involved in the development of kidneys, liver, pancreas, intestine and urogenital tract. Patients can present with distinctive but highly variable clinical features. The aim of this study is to evaluate the clinical, biochemical and radiological variability of HNF1β variants and the challenge of management on th...

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ea0056p379 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Maternally inherited diabetes and deafness (MIDD): the many faces of the same disease in a Spanish family

Silva Carlos , Garcia Elena , Villa Gema , Martin Alba , Males David , Martinez Guillermo , Leon Miguel

Introduction: Maternally inherited diabetes and deafness (MIDD), is a rare entity. Most commonly, it is related to a point mutation in the mitochondrial DNA (mtDNA) at position 3243 (m.3243A>G) encoding the gene for tRNA. A high index of suspicion is required for the diagnosis due to a wide heterogeneity in its clinical presentation which reflects different levels of mutated mtDNA among mitochondria in a given tissue (heteroplasmy). Thyroid cancer risk has never been speci...

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ea0056p380 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

The detection of disordered eating risk in patients with type 2 diabetes mellitus

Labashova Veranika , Shepelkevich Alla , Dydyshka Yulia , Kozlova Alena

Background and aims: Type 2 diabetes is strongly associated with obesity as the major potentially modifiable risk factor. Apart from total caloric intake, certain eating patterns have been associated with the risk of diabetes and insulinoresistance. Researchers have found that specific groups in the community may be at increased risk of eating disorders, including people with diabetes and those who are obese. The aim of the study was to detect the risk of disordered eating in ...

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ea0056p381 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Gestational diabetes and weight gain in outpatient practice

Zabuliene Lina , Einikyte Ruta , Kersulyte Daiva , Kutkauskiene Jelena , Urboniene Jurgita

Hyperglycaemia is one of the most common medical conditions women encounter during pregnancy. The occurrence of gestational diabetes mellitus (GDM) is rising and it represents an important modifiable risk factor for adverse pregnancy outcomes. Similar to GDM, excessive weight gain is associated with a number of undesirable consequences for both the mother and neonate. The aim of this study was to evaluate prevalence of GDM in outpatient practice and investigate associations be...

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ea0056p382 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Oral glucose tolerance test in reclassification of gestational diabetes after delivery – results from portuguese national registry

Cunha Nelson , Gomes Leonor , Paiva Sandra , Ruas Luisa , Oliveira Diana , Lages Adriana , Ventura Mara , Fadiga Lucia , Catarino Diana , Almeida Maria Ceu , Carrilho Francisco

Introduction: Gestational diabetes (DG) is associated with higher risk of diabetes mellitus (DM), and its recommended to perform an oral glucose tolerance test (OGTT) with 75 g after delivery to its reclassification. However, not all scientific societies recommend it.Aim: To evaluate glucose tolerance with OGTT after delivery in women with DG and the risk factors to glucose intolerance in glycaemia at 120′.Methods: Retr...

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ea0056p383 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Relationship between circulating 25-hydroxyvitamin D and glucose homeostasis in women with postmenopausal osteoporosis

Avila-Rubio Veronica , Garcia-Fontana Beatriz , Novo-Rodriguez Cristina , Cantero-Hinojosa Jesus , Munoz-Torres Manuel

Context: Postmenopausal osteoporosis (PMO) is associated with other comorbidities such as cardiovascular disease and impaired glucose homeostasis. Vitamin D insufficiency is highly prevalent, and may be a common link between these disorders. Recently, it has been shown that vitamin D may be involved in insulin resistance; however, this relationship has not been well evaluated in women with PMO.Objective: To assess the relationship between circulating lev...

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ea0056p384 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Demographic and clinical factors associated with having ischemic heart disease as a multiple contributing causes of death among diabetes mellitus deaths in the United States and Brazil

Sugai Maaya Kita , Nomura Shuhei , Gilmour Stuart , Stevens Gretchen A , Shibuya Kenji

Introduction: Between-country comparability and validity of mortality statistics is a global public health challenge, especially for cause-of-death assignment of diabetes mellitus (here after diabetes) in relation to cardiovascular disease. The multiple contributing causes of death (MCD) representing comorbidity are not used to classify mortality cause, as the underlying cause of death (UCD) becomes the cause-of-death. Diabetes increases risk of ischemic heart disease (IHD). T...

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ea0056p385 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Gestational diabetes – association of lipid profile in pregnancy with post-partum dysglycemia

Paredes Silvia , Fernandes Aline , Pereira Maria Lopes

Introduction: Lipid profile characterization in women with gestational diabetes mellitus (GDM) and its impact on post-partum dysglycemia remains to elucidate. The aim of this study was to evaluate lipid profile in women with GDM during pregnancy and 8 weeks after and to study its correlation with glycemic control.Methods: This study was carried out in a central hospital in Portugal. All women with GDM diagnosed from January/2014 to December/2015 were enr...

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ea0056p386 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Changes in the glutathione system in patients with impaired carbohydrate metabolism

Shyshko Volha , Mokhort Tatjana , Buko Inna , Konstantinova Elena , Tsapaeva Natalia , Sazonava Alena

Introduction: Many studies have found that markers of oxidative stress (OS) are significantly increased in diabetes mellitus, but only a limited number of studies describe the disturbance of OS in pre-diabetes.Objective: To study the state of the glutathione system in patients with disorders of carbohydrate metabolism and concomitant diseases of the cardiovascular system (CVS).Materials and methods: 181 patients were included under...

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ea0056p387 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

The effect of the dopamine agonist cabergoline on insulin sensitivity in the skeletal muscle: an in vitro study in a mouse cell model demonstrating mediation by serotoninergic receptors

Negri Mariarosaria , Pivonello Claudia , Gennaro Gilda Di , Angelis Cristina de , Simeoli Chiara , Iacuaniello Davide , Nettore Immacolata Cristina , Macchia Paolo Emidio , Muscogiuri Giovanna , Colao Annamaria , Pivonello Rosario

Insulin resistance (IR), characterized by an impairment of target tissues to insulin responsiveness, is the core defect preceding diabetes. Preclinical and clinical data have suggested a role for the dopaminergic system in glucose homeostasis control. The aim of the current study was to investigate the role of the dopamine agonist cabergoline (CAB), displaying high affinity for dopamine type 2 (DR2) receptor and low affinity for serotonin receptors (5-HTRs), in the regulation ...

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ea0056p388 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Eating habits, food choices and physical activity in adult patients with type 1 diabetes mellitus

Barmpa Eleftheria , Tsiouma Christina , Bargiota Alexandra

Introduction: Eating habits, food choices and exercise affect glycaemic control in patients with Type 1 Diabetes Mellitus (T1DM). The purpose of this study was to evaluate eating behaviors, food choices and the level of physical activity in patients with T1DM.Methods/design: A random sample of 84 patients (M/F: 31/53) with T1DM, aged 34+11.9 years, living in central Greece, were individually interviewed. Food consumption was assessed by a semi-q...

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ea0056p389 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Preconception management in type 2 diabetes mellitus (T2DM): there is still much work to do

Berges-Raso Irene , Albert Lara , Capel Ismael , Cano-Palomares Albert , Casamijana Laia , Mazarico Isabel , Luchtenberg Maria Florencia , Costa Jordi , Rigla Mercedes

Background: Preconception planning is essential for a successful pregnancy in women with pregestational diabetes,although many women still do not plan their pregnancies. The rapid outbreak of T2DM among the general population, including women of childbearing age, is one of the largest public health issues. The aim of this study is to describe time trends in preconception planning, obstetric and perinatal outcomesduring the past 8 years in ourpregestational care unit, focusing ...

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ea0056p390 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Kinky and sparse hair as an associated finding inmaternally inherited diabetes and deafness

Karaguzel Gulay , Cebi Alper Han , Sag Elif

Background: Maternally inherited diabetes and deafness (MIDD) is a rare form of diabetes due to defects in mitochondrial DNA (mtDNA). Maternal transmission of diabetes and neurosensorial deafness are the main clinical features of MIDD followed by other mitochondrial disorders, myopathies, and macular dystrophy. 3243 A>G is the mutation most frequently associated with this condition, but also other mtDNA variants have been linked with MIDD. We describe the case presenting w...

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ea0056p391 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Stiff - person syndrome in an old woman with late onset type 1 diabetes mellitus

Luchtenberg Maria Florencia , Capel Ismael , Mazarico Isabel , Cano Albert , Albert Lara , Casamitjana Laia , Subias David , Martinez Jose Miguel , Caixas Assumpta , Rigla Mercedes

Introduction: Stiff person syndrome (SPS) is a rare neurological disease resulting in stiffness and spasm of muscles and, as a consequence, severely impaired ambulation. Pathophysiology of the disease is based on an increased muscle activity caused by the decreased level of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) due to an autoimmune attack against glutamic acid decarboxylase (GAD); enzyme which is also one of the main autoantigens of type 1 diabetes mel...

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ea0056p392 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Autoimmune hypoglycemia in a patient with slow type 1 diabetes

Ilham Bouizammarne , Mghari Ghizlane El , Ansari Nawal El

Introduction: Hypoglycemia is rarely due to an auto-immune etiology, which is the presence in the serum of the patient of anti-insulin or anti-insulin receptor antibodies. The present case is of a slow type 1 diabetic patient in whom the autoimmune origin of repeated hypoglycemia was found.Case: A 58 years old female patient, Who is a slow type 1 diabetes carrier, and has been on premixed human insulin for 4 years, the patient presented repeated episodes...

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ea0056p393 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Insulin resistance in diabetes mellitus type 1, and its association with cardiovascular disease, sex hormones

Simoniene Diana , Velickiene Dzilda , Platukiene Aksana

Objective: The aim of the study was to determine frequency of insulin resistance, in individuals with type 1 diabetes mellitus and the link between insulin resistance and cardiovascular disease, sex hormones. The task of the research is to determine the frequency of insulin resistance among people with diabetes mellitus type 1. To determine association between eGDR and age, sex, cardiovascular disease, chronic complications of diabetes and sex hormones. To determine associatio...

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ea0056p394 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Mitochondrial diabetes in 40 patients belonging to 30 Tunisian families: phenotypic and genotypic heterogeneity

Safi Wajdi , Tabbabi Mouna , Hadj Kacem Faten , Gargouri Imene , Elleuch Mouna , Sassi Salwa , Mnif Feki Mouna , Fakhfakh Faiza , Abid Mohamed

Introduction: Mitochondrial diabetes (MD) is characterized by a broad spectrum of phenotypic and genotypic involvement. Through a cohort study of 40 patients with DM, we tried to correlate this diversity of phenotypic expression with the biomolecular substratum of the mitochondrial genome in the Tunisian population.Results: Epidemiologically and anthropometrically, our series fits the literature data with age at 31.6 years (552), female predominanc...

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ea0056p395 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Hyperandrogenaemia in women with type 1 diabetes mellitus; associations with lipids and lipoprotein particle size, and early vascular disease

Gunness Anjuli , Pazderska Agnieszka , Ahmed Mohamed , McGowan Anne , Phelan Niamh , Boran Gerard , Taylor Angela , O'Reilly Michael , Arlt Wiebke , Moore Kevin , Ann Behan Lucy , Sherlock Mark , Gibney James

Hyperandrogenaemia and polycystic ovary syndrome (PCOS) are common in women with Type 1 diabetes, but it is not known if they contribute to increased cardiovascular risk. We aimed to compare associations between androgen levels, lipid variables and early atherosclerosis in reproductive-age women with and without T1DM. 87 (16 with PCOS) women with T1DM (mean±SD; age 28.7±6.1yrs, BMI 25.4±4.4kg/m2), and 87 (16 PCOS) nondiabetic women (mean±SD; age ...

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ea0056p396 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Association of the FTO gene rs9939609 polymorphism with carbohydrate metabolism disorders in the Republic of Tatarstan

Valeeva Farida , Ahmetov Ildus , Kiseleva Tatyana , Khasanova Kamilya , Sozinova Elizaveta , Valeeva Elena

Aim: To investigate the possible association of the FTO gene rs9939609 polymorphism with different disorders of carbohydrate metabolism in residents of the Republic of Tatarstan.Materials and methods: A total of 237 patients with a single history of hyperglycemia were examined. They underwent an oral glucose tolerance test on a BS-200E Mindray analyzer. 198 patients from the whole cohort had various disorders of carbohydrate metabolism, so they were incl...

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ea0056p397 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Reactive hypoglycaemia – a debilitating condition

Grant Bonnie , Bonner Caoimhe , Lee Yun-ni , William Augustine , Tanday Raj , Hawkins Anna , Casey Edel , Nikookam Khash

Although there are no formal diagnostic criteria, reactive hypoglycaemia is a term generally used to describe hypoglycaemia occurring within a few hours after meal intake where other causes of hypoglycaemia such as medications, cortisol deficiency and insulinoma have been excluded. Although this is considered a benign, easily managed condition here we present three cases of reactive hypoglycaemia with significant debilitating symptoms. The first case is a 26-year-old man who w...

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ea0056p398 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Abstract withdrawn....

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ea0056p399 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Metabolic syndrome in patients with latent autoimmune diabetes of adults (LADA)

Zahra Zaher Fatima , Elmghari Ghizlane , Elansari Nawal

Introduction: Latent autoimmune diabetes in adults (LADA) is an endocrine disorder characterized by a progressive destruction of pancreatic beta cells by an autoimmune mechanism leading to absolute insulin deficiency. However, recent studies have shown the presence of a certain degree of insulin resistance in LADA patients, hence the possibility of the existence of a metabolic syndrome in these patients. The purpose of our work is to evaluate the presence of metabolic syndrome...

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ea0056p400 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Gestational diabetes and postpartum follow up

Driouich Yasmine , Aziz Siham El , Bensbaa Salma , Chadli Asma

Introduction: Gestational diabetes mellitus (GDM) is an important public health issue because of its frequency and its risk of progression to T2DM. Risk of subsequent type 2 diabetes is associated with quality screening and to certain risk factors.Objective: The aim of our study was to assess the evolving risk of GDM to type 2 diabetes, and to find its significant predictive factors.Methods: We report a retrospective study from Jan...

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ea0056p401 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Glycemic variability and diabetes-related antibodies titer at diagnose in type 1 diabetic patients: is there a correlation?

De Sousa Lages Adriana , Cardoso Luis , Baptista Carla , Barros Luisa , Oliveira Patricia , Oliveira Diana , Ventura Mara , Cunha Nelson , Catarino Diana , Fadiga Lucia , Carrilho Francisco

Introduction: Type 1 Diabetes (DM1) is associated with a destructive autoimmune process of pancreatic b-cells. The presence of anti-islet cells (ICA) antibodies (Ab), as well as for distinctive antigens GAD65, IA2 or Insulin (IAA) - is related to the disease development.Aim: To evaluate the effect of DM1 antibodies on the measures of glycemic variability (GV) obtain through continuous glucose monitoring (CGM).Materials and m...

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ea0056p402 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Major adverse cardiovascular events and in-hospital outcomes in patients with diabetes

Neves Celestino , Sergio Neves Joao , Oliveira Sofia Castro , Pereira Miguel , Oliveira Ana , Carvalho Davide

Background: Diabetes is an important risk factor for major adverse cardiovascular events (MACE). Although the increased risk for MACE is well known, the impact on the in-hospital outcomes remains incompletely understood. Our aim was to evaluate the interrelation between diabetes and MACE in a central hospital in the North of Portugal between 2009 and 2015.Methods: We evaluated retrospectively the hospitalizations due to MACE including stroke or transient...

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ea0056p403 | Diabetes (to include epidemiology, pathophysiology) | ECE2018

Screening for autoimmune endocrinopathiesAt 300 insulin-dependent diabetics type1

Kaidi FZ , El Aziz S. , Mjabber A. , Chadli A. , Kaidi Fatima Zahra

Introduction: Type 1 diabetes is an autoimmune disease that can be associated with other autoimmune endocrinopathies. Occurrence of these autoimmune endocrinopathies increases the management of diabetes and affects the quality of life of patients. The aim of our study was to clarify the prevalence of endocrine autoimmune diseases associated with diabetes type 1 and their clinical characteristics.Patients and methods: A descriptive analytical and retrospe...

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20th European Congress of Endocrinology

BiosciAbstracts