Searchable abstracts of presentations at key conferences in endocrinology
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20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

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ECE 2018, 19 - 22 May 2018; Barcelona, Spain

Poster Presentations: Reproductive Endocrinology

Endocrine tumours and neoplasia

ea0056p910 | Endocrine tumours and neoplasia | ECE2018

Resveratrol inhibits DHT-induced metastasis of prostate cancer through interfering with the AR and CXCR4 pathway

Jang Yin-Gi , Hwang Kyung-A , Choi Kyung-Chul

Prostate carcinoma is one of the most common malignancies and the second most common cause of cancer-related deaths in men world-wide and is affected by the action of dehydrotestosteron (DHT) via androgen receptor (AR). Resveratrol as a phytochemical in grapes and red wine has diverse effects such as anti-inflammation, anti-oxidant and anti-cancer. CXCR4 as a chemokine receptor has been found to be upregulated in cancer metastasis and has been used as a prognostic marker in va...