ECE2018 Poster Presentations: Thyroid Thyroid cancer (88 abstracts)
Thyroid cancer prevalence and pathological features in thyroidectomy patients – five years experience
Oana-Stefana Enache 1 , Sorina Martin 1, , Oana Ion 3 , Andreea Grigore 4 , Irina Bojoga 1, , Ovidiu Parfeni 1 , Anca Sirbu 1, , Carmen Barbu 1, , Cosmin Giulea 5, , Adrian Miron 5, , Florin Andrei 7 & Simona Fica 1,
1Elias Hospital, Endocrinology Department, Bucharest, Romania; 2Carol Davila University of Medicine and Pharmacy, Endocrinology Department, Bucharest, Romania; 3Fundeni Clinical Institute, Nephrology Department, Bucharest, Romania; 4Fundeni Clinical Institute, Gastroenterology Department, Bucharest, Romania; 5Elias Hospital, Surgery Department, Bucharest, Romania; 6Carol Davila University of Medicine and Pharmacy, Surgery Department, Bucharest, Romania; 7Elias Hospital, Pathology Department, Bucharest, Romania.
Objectives: In the last decades, thyroid cancer incidence has increased all over the world. This may be due to heightened medical surveillance and more addressability to surgery, as many cancers are diagnosed while under 1 cm. The aim of our study was to obtain data about the prevalence and histological subtypes of primary thyroid carcinoma in patients undergoing thyroidectomy.
Materials and methods: We retrospectively analysed the files of 953 patients who underwent thyroidectomy in our surgery department between January 2012- December 2017. Anthropometric, biologic and imagistic data, indication of thyroid surgery, surgical procedures and pathology results were recorded.
Results: 222 (23 .29%) patients had a diagnosis of primary thyroid carcinoma. The primary indications for thyroid surgery included: 5 (2.3%) Graves’ disease and nodular goiter, 181 (81.5%) multinodular goiter, 23 (10.4%) uninodular goiter and 13 (5.9%) thyroid cancer. The mean age at diagnosis was 52.49±13.79, range 20-83 years, but 61 (27.47%) were diagnosed before the age of 45 years. The female to male ratio was 180:42=4.28. The surgical procedure was lobectomy in 3 and total thyroidectomy in the remaining 219 patients. 207 (93.24%) suffered from differentiated thyroid carcinoma [194 (87.38%) papillary, 13 (5.85%) follicular], 7 (3.15%) from medullary thyroid carcinoma, 4 (1.8%) from poorly differentiated and 4 (1.8%) from anaplastic thyroid carcinoma. Multifocality was present in 62 (27.9%) patients. Pathological tumor stage was: T1 in 99 (44.6%), T2 in 38 (17.1%), T3 in 76 (34.2%) and T4 in 9 (4.1%) patients. 78 (35.1%) patients had tumors of 1 cm or less in diameter. 79 (35.6%) patients associated histopathologic chronic autoimmune thyroiditis.
Conclusions: One in five patients who underwent thyroidectomy had a thyroid cancer. This might be due to a real increased incidence of thyroid cancer or just a result of better selection of patients for surgery and diagnose of microcarcinomas that otherwise would have gone unnoticed. Papillary thyroid carcinomas constituted the vast majority of these neoplasms, this being usually associated with an iodide-sufficient area.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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