Searchable abstracts of presentations at key conferences in endocrinology
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20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

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ECE 2018, 19 - 22 May 2018; Barcelona, Spain


Environmental effects on endocrine functions

ea0056s4.1 | Environmental effects on endocrine functions | ECE2018

Developmental exposures to endocrine disrupting chemicals (EDCs) reprogram the epigenome to increase risk for hormone-dependent cancers and other diseases of adilthood

Walker Cheryl

While organisms have evolved to maintain the fidelity of their genome, the epigenome, in contrast, is inherently plastic, with extensive remodeling required during normal development. This epigenomic plasticity plays a role in preparing the developing organism for its adult environment. The epigenome is able to sense environmental cues, providing an opportunity for adaptive changes during development that can provide a later-life survival advantage. However, epigenomic plastic...

ea0056s4.2 | Environmental effects on endocrine functions | ECE2018

Iodine deficiency in pregnancy and development of offspring

Trofimiuk-Muldner Malgorzata

Iodine as the main component of thyroid hormones is an essential micronutrient for proper neurodevelopment. According to the WHO, its deficiency is the most common cause of preventable brain damage worldwide. Although most severe forms of iodine malnutrition have almost been eliminated, mild-to-moderate iodine deficiency is still very common, affecting approximately two billions people worldwide. Due to increased iodine requirements during gestation, iodine deficiency in pregn...

ea0056s4.3 | Environmental effects on endocrine functions | ECE2018

Environmental contaminants and endocrine disruption: the story of obesogens

Sousa Ana Catarina

According to the World Health Organization, obesity is one of the most important public health challenges of the 21st Century. There is no doubt that excessive calories intake and lack of exercise, are important factors, and that genetics plays a critical role. However, because genes in the population do not change fast enough, other causes must be involved. The involvement of other causes in the etiology of obesity is further strengthened by the fact that obesity is increasin...