Endocrine Abstracts

Background: 50% of patients with osteogenesis imperfecta (OI) will have dental involvement of some degree including dentinogenesis imperfecta and a severe malocclusion. OI is the most common inherited disorder of bone fragility in children, increasing fracture risk 100-fold.

Aim: To assess the utilisation of tertiary dental services by children and young people with OI attending a supra-regional multidisciplinary OI service and review of the pathology identified and interventions undertaken.

Design: Case notes review of the current caseload of children and young people (0–18 years) with OI at an OI specialist centre. Primary outcome was if an initial dental assessment was arranged in a tertiary dental centre and the corresponding attendance.

Results: Only 49% received a dental assessment. 82% attended the appointment, 18% failed to attend multiple appointments. Those travelling >100 miles had a DNA rate of 47%. Greater the OI severity, the higher the incidence of DI; 7% incidence in Type I OI and 50% in Type III. 48% received bisphosphonate therapy. 33% required GA for extraction of carious teeth.

Conclusion: Due to the prevalence of DI, severe malocclusion and the increased incidence of dental caries necessitating extraction under GA, coupled with the increased use of bisphosphonates, all patients with OI should receive a formal dental assessment in tertiary care.