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Endocrine Abstracts (2018) 56 GP89 | DOI: 10.1530/endoabs.56.GP89

1Gulhane Training and Research Hospital, Department of Endocrinology and Metabolism, Ankara, Turkey; 2Gulhane Training and Research Hospital, department of Psychiatry, Ankara, Turkey.

Introduction: Elevated depressive symptoms and depressive disorders affect one in four patients with type 1 or type 2 diabetes (1). Thus, routine screening for depressive symptoms is indicated in this high-risk population. Current guidelines all recommend screening for depression in diabetic population(2). The Patient Health Questionnaire-9 (PHQ-9) is a valid screening tool for depression in individuals with diabetes (3). There is no specific data about the prevalence of depressive disorders diabetic population of Turkey. Therefore, we planned this study to investigate depressive disorder incidence in a small group of diabetic patient population.

Methods: The demographic and laboratory parameters including glycated hemoglobin (HbA1c), lipid levels and body-mass indexes (BMI) were measured and PHQ-9 questionnaire was applied to all the diabetic patients admitted our endocrinology department and accepted to participate in the study. We used a cut-off point of 10 and above as high risk for depression in PHQ-9 questionnaire.

Results: A total of 552 patients with diabetes (mean age 58.548±12.13) were enrolled in the study. Based on the predefined PHQ-9 cut-off value, 87 (16%) participants had depressive disorders. The patients with depressive disorders had worse HbA1c (7.91±2.05 vs. 8.52±2.44 in depression negative and positive groups, respectively; P=0.012), BMI (31.54±5.72 vs. 34.17±7.96 in depression negative and positive groups, respectively; P=0.005). Although statistically unimportant, LDL-C, non-HDL-C and FBG levels were also higher in the depressive disorder positive group. Patients of whom HbA1c was above target (uncontrolled diabetes) had higher PHQ-9 scores and there was a positive correlation detected between PHQ-9 score and HbA1c values (r=0.108, P=0.011).

Conclusion: Depressive disorders prevalence is higher than expected in diabetic population. As recommended by guidelines every diabetic patient should be screened for depressive disorders periodically. PHQ-9 questionnaire is a practical and useful material for screening depressive disorders in diabetic patients.

Volume 56

20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

European Society of Endocrinology 

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