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Endocrine Abstracts (2018) 56 P1022 | DOI: 10.1530/endoabs.56.P1022

ECE2018 Poster Presentations: Thyroid Thyroid (non-cancer) (105 abstracts)

Correlation between cytologic results and thyroid autoantibodies, calcitonin, and thyroid function tests in patients with thyroid nodules

Pinar Karakaya 1 , Bahar Pehlivan 2 , Meral Mert 1 , Bülent Yaprak 2 , Yildiz Okuturlar 2 , Sema Doğançiftçi 1 , Cevher Akarsu 3 , Ahmet Cem Dural 3 & Abdülbaki Kumbasar 2

1Bakırköy Dr. Sadi Konuk Training and Research Hospital Endocrinology Department, Istanbul, Turkey; 2Bakırköy Dr. Sadi Konuk Training and Research Hospital Internal Diseases Department, Istanbul, Turkey; 3Bakırköy Dr. Sadi Konuk Training and Research Hospital General Surgery Department, Istanbul, Turkey.

Aim: Fine needle aspiration biopsy (FNAB) is currently a widely accepted screening procedure in diagnosis of thyroid nodules, there has been confusion related to diagnostic terminology in the assessment of samples. This confusion has been caused by multiple category names, descriptive reports without assigning to a category, and different terminologies used for surgical pathology. We aimed to evaluate correlations between US characteristics, cytologic results of FNAB, and thyroid antibodies, calcitonin, and thyroid function tests in patients presented with thyroid nodules, and to contribute in diagnosis, treatment, and patient follow-up.

Methods: A total of 1639 patients with thyroid nodules who applied to outpatient clinic of endocrinology between dates April and May 2017, had FNAB under US guideline, and their pathologic evaluation was performed according to Bethesda classification. Serological and hormonal tests were also performed for each patient.

Results: The mean age of study group was 50 (range interval=14–90) years. The median of node-diameter1 was 17.5 (range=1–51) mm, and median of node-diameter 2 was 12 (range=8–33) mm. Of US characteristics, echogenicity, microcalcification, irregular borders, and solitary nodules were determined in 4.4%, 54%, 71.2%, and 86.6% of cohort respectively. Elevated anti-TPO was determined in 64.6%. Cytologic readings were reported as 15.8% nondiagnostic, 53.8% atypia of undetermined significance/follicular lesion of undetermined significance, 28.8% benign, 0.4% suspicious for follicular nodule, and 1.2% malign.

Conclusion: FNAB, high resolution US findings, and sensitive thyrotropin levels are the mainstay to determine further clinical approach in patients with thyroid nodules.

Volume 56

20th European Congress of Endocrinology

Barcelona, Spain
19 May 2018 - 22 May 2018

European Society of Endocrinology 

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