ECE2018 Poster Presentations: Thyroid Thyroid cancer (88 abstracts)
Thyroglossal duct cyst papillary carcinoma: case report and review of literature
M Delgado 1 , J Paz 1 , E Linares 1 , J Gonzales 1 , R López 1 , A Ponce 1 , F Cabrera 1 , K Calderón 1 , S Regalado 1 , J Casusol 1 , M Castro 1 , C Reaño 1 , I Giles 1 , J Corrales 1 , S Sáenz 1 , Marialejandra Delgado Rojas 2 , Edgardo Linares Reyes 3 & Jose Luis Paz Ibarra 4
1Endocrinology Service-Hospital Almanzor Aguinaga- Es salud-. Lambayeque-Perú; 2Hospital Almanzor Aguinaga Asenjo, Chiclayo, Peru; 3Hospital Belen, Trujillo, Peru; 4Hospital Edgardo Rebagliatti, LIma, Peru.
Objective: To report a rare case of papillary thyroid carcinoma (PTC) in a thyroglossal duct cyst (TGDC).
Case report: A 34-year-old peruvian male came to our hospital with a complaint of a swelling cervical mass in the anterior central side of the neck, which was growing since 6 months earlier. The patient had no significant past medical, surgical history and was completely asymptomatic. He denied any family history of thyroid disease or history of head and neck irradiation. Physical exam reveal a nontender, not much mobile and semi-solid neck mass measuring 5 cm in the suprahyoid median line, with some phlogosis signs. Laboratory examinations include: TSH 3.21 uIU/ml, T4L 1.0 ng/dl and Anti-TPO/AbTg (-). Cervical ultrasonography revealed homogenous thyroid gland with normal dimensions. RTL: hypoechogenic nodule with defined edges of 9×7 mm soft consistency to elastography. In the anterior central side of the neck, suprahyoid cystic image with sediment and thick calcifications was observed, measuring 48×39×59 mm, with a volumen of 58.5 cc. CT: encapsulated, lobulated and bilobed cystic lesion with small internal calcifications measuring 33×30×15 mm, located in the midline cervical, as well as multiple cervical lymph nodes enlargement, the largest in the right carotid side. FNAB of cervical tumor: malignant neoplasm of papillary aspect of probable thyroid origin. Sistrunk procedure was performed, during which we found a 7 cm mass, with necrosis of the anterior side and thinning of the skin, as well as a superficial pre-laryngeal lymph node. Histopathology of the mass demostrated a PTC papillary and follicular variant in TGDC, with infiltrative borders and capsular and bone invasion, measuring in greatest dimension 1 cm, excision margins free of neoplasia. Presence of neoplasic invasion of lymphatic vessels. Lymph node and submental region free of neoplasia. Patient underwent a total thyroidectomy that reported absence of malignant lesion. Patient is waiting for ablative radioiodine.
Conclusion: The clinical presentation of PTC in the TGDC in the early phase; It presents an anterior cervical mass of rapid grow, fixed, indurated, irregular, accompanied by lymphadenopathies in the upper jugular group. The role of total thyroidectomy is still controversial, as is postoperative adjuvant treatment. The prognosis of PTC of the TGDC is good.
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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