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Endocrine Abstracts (2019) 61 OU8 | DOI: 10.1530/endoabs.61.OU8

Southmead Hospital, North Bristol NHS Trust, Bristol, UK.


The evidence base for obesity surgery in the context of diabetes will be briefly presented introducing the concept of surgery for the metabolic syndrome. The shift from treating morbid obesity to treating obesity associated morbidity will be discussed. Data on long-term outcomes after weight loss surgery will be presented demonstrating that recurrence of type 2 diabetes following initial remission is an issue. The need for intensive treatment of type 2 diabetes postoperatively with reduction in cardiovascular risk will be highlighted. The paradigm of cancer treatment with multimodal treatment, surgical and medical will be discussed. Comparative data of best medical therapy compared to best medical therapy combined with weight loss surgery will be presented. The need to focus on hard endpoints such as micro-vascular complications as an outcome measure after weight loss surgery will be suggested, as with all other treatment modalities used for type 2 diabetes. The shift of the focus from weight loss maintenance to obesity associated disease control will be highlighted.

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