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21st European Congress of Endocrinology

Lyon, France
18 May 2019 - 21 May 2019

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18-21 May 2019, Lyon, France

Guided Posters

Thyroid Nodules and Cancer 2

ea0063gp254 | Thyroid Nodules and Cancer 2 | ECE2019

Recurrent laryngeal nerve liberation technique for phonation recovery

Dzodic Radan , Santrac Nada , Markovic Ivan , Buta Marko , Stankovic Predrag

Introduction: Recurrent laryngeal nerve (RLN) dysfunction is a major complication in thyroid surgery, caused commonly by thermal damage, transection or misplaced ligations. It can also be caused by RLN distension by thyroid tumors or thyroid goiter. Permanent paralysis decreases significantly quality of life and should be treated. Some surgical techniques can provide improvement in phonation, even complete recovery. The aim of this study was to analyze usefulness of RLN libera...

ea0063gp255 | Thyroid Nodules and Cancer 2 | ECE2019

Are clinicopathological features of isthmic thyroid nodules different from nodules located in thyroid lobes?

Dellal Fatma Dilek , Topaloglu Oya , Baser Husniye , Dirikoc Ahmet , Altınboga Aysegul Aksoy , Kilinc Ibrahim , Ersoy Reyhan , Cakir Bekir

Aim: Although thyroid nodules located in isthmus were less frequent, papillary thyroid cancer in this location was reported to be more aggressive in some studies. Our aim was to evaluate hormonal, ultrasonographic, and cytopathologic features of nodules located in isthmus (isthmic nodules).Material and methods: Data of patients who underwent thyroidectomy between 2006–2014 were reviewed retrospectively. Hormonal, ultrasonographic, and cytopathologic...

ea0063gp256 | Thyroid Nodules and Cancer 2 | ECE2019

Impact of age at the diagnosis of radioiodine resistance in differentiated thyroid cancer patients

Saie Clotilde , Wassermann Johanna , Mathy Elise , Tezenas Sophie , Chereau Nathalie , Leenhardt Laurence , Buffet Camille

Background: Clinical predictors of survival of radioiodine-refractory differentiated thyroid cancer (RR-DTC) are poorly described. Age has been identified as a major prognostic factor in differentiated thyroid cancer. We asked whether age was a valuable predictor of poor prognosis in RR-DTC.Patients and method: This single centre, retrospective study enrolled all patients diagnosed with a RR-DTC between 1991 and 2017. The primary end point was overall su...

ea0063gp257 | Thyroid Nodules and Cancer 2 | ECE2019

Effects of hospital volume on clinical outcomes after thyroidectomy - a Swiss nation-wide study

Ebrahimi Fahim , Kutz Alexander , Christ Emanuel , Schuetz Philipp , Mueller Beat

Background: Epidemiologocal data suggest an continuous increase in thyroid carcinoma diagnosis. Therefore, thyroidectomy rates are projected to increase world-wide in exponential scale. In Switzerland, the institutional number of thyroidectomies varies, however there is no data yet on the association between institutional thyroidectomy volume and clinical outcome.Methods: Cross-sectional analysis of adult inpatients in Swiss hospitals using a nation-wide...

ea0063gp258 | Thyroid Nodules and Cancer 2 | ECE2019

Predictors of malignancy in thyroid FNA classified as high-risk indeterminate lesions (TIR3B): combining ultrasonographic and cytology features

Cozzolino Alessia , Pozza Carlotta , Faggiano Antongiulio , Pofi Riccardo , Ascoli Valeria , Di Gioia Cira , Bosco Daniela , Lenzi Andrea , Isidori Andrea M , Giannetta Elisa , Gianfrilli Daniele

Introduction: The new Italian cytological classification of thyroid nodules published in 2014 has replaced the TIR3 ‘indeterminate’ category into two subcategory with different risk of thyroid cancer (TC): TIR3A, low-risk indeterminate lesion and TIR3B, high-risk indeterminate lesion. The aim of our study was to describe the incidence of TIR3B in a large prospective cohort of patients, the risk of TC, and its correlation with anamnestic, ultrasonographic (US) and cyt...

ea0063gp259 | Thyroid Nodules and Cancer 2 | ECE2019

Sentinel lymph node biopsy using methylene blue dye in clinically N0 papillary and medullary thyroid carcinomas for decision on one-time lateral neck dissection

Santrac Nada , Markovic Ivan , Goran Merima , Buta Marko , Pupic Gordana , Dzodic Radan

Introduction: Surgical management of clinically N0 (cN0) patients with thyroid carcinomas remains debatable due to various reported frequencies of lymph node (LN) metastases. The aim of this paper was to present usefulness of sentinel lymph node biopsy (SLNB) of jugulo-carotid regions after methylene blue dye (MBD) mapping in intraoperative selection of cN0 patients with papillary and medullary thyroid carcinomas for one-time lateral neck dissection (LND).<p class="abstext...

ea0063gp260 | Thyroid Nodules and Cancer 2 | ECE2019

Factors influencing nodular goiter – An analysis of the growth rates in long-term follow-up patients

Kunori Takao , Nemoto Noriko , Kawaguchi Shinya , Hashimoto Akihiko , Yoshida Hiroshi , Shiraso Satoru , Fujikawa Nanako , Shinya Fumiaki

Background: Nodular goiter (NOD) is one of the most common disease (69% in our thyroid clinic). Although the nodular growth is generally slow, it may be influenced by thyroid hormones, autoimmunity or other factors. The analysis may contribute to predict the outcomes.Patients and methods: 2,213 Japanese patients (2007–2018; Fukushima coast area) with NOD were enrolled in this study. Mean observation period was 6.4 years with 7 visits (1–50). Th...

ea0063gp261 | Thyroid Nodules and Cancer 2 | ECE2019

Evaluating effects of thyrotrophin receptor antibody positivity on cytology and histopathology in patients with graves disease

Baser Husniye , Topaloglu Oya , Aydın Cevdet , Yazicioglu Mustafa Omer , Dogan Hayriye Tatli , Ersoy Reyhan , Cakir Bekir

Aim: It has been reported that thyrotrophin receptor antibody (TRAb) is associated with frequency and aggressiveness of thyroid cancer in patients with Graves disease (GD). However, there is not any data regarding the effects of TRAb on cytology and histopathology results of patients with nodular GD. Thus, the aim of the present study is to evaluate the effects of TRAb on cytology and histopathology results in patients with nodular or multinodular thyroid disease on the basis ...

ea0063gp262 | Thyroid Nodules and Cancer 2 | ECE2019

Classification of thyroid nodules by ultrasound in clinical practice: the added value of the judgment of the skilled endocrinologist

Madeo Bruno , Brigante Giulia , Ansaloni Anna , Taliani Erica , Kaleci Shaniko , Monzani Maria Laura , Simoni Manuela , Rochira Vincenzo

Background and aim: Several ultrasound (US) classifications for thyroid nodules have been proposed. Since most of them are hardly applicable in clinical practice, we set up the Modena US Thyroid Classification (MUT) that stratifies the risk of malignancy considering both knowledge derived from scientific literature and clinician subjective impression. The aim of the present study was to test the diagnostic accuracy of different thyroid US classification systems, AACE/ACE-AME, ...

ea0063gp263 | Thyroid Nodules and Cancer 2 | ECE2019

Predictive factors of short and long-term vandetanib response in locally advanced or metastatic medullary thyroid cancer: a single center experience

Valerio Laura , Bottici Valeria , Matrone Antonio , Tacito Alessia , Romei Cristina , Piaggi Paolo , Elisei Rossella

Objectives: Vandetanib (V) is an important drug in the metastatic medullary thyroid cancer (MTC) treatment. The objective of this study was to evaluate the presence of predictors of V response, in short and long period, in locally advanced or metastatic MTC patients (pts).Methods: Seventy-nine locally advanced or metastatic MTC pts with progressive or symptomatic disease, referred to our Center between 2007 and 2018 and already treated surgically and wit...

ea0063gp264 | Thyroid Nodules and Cancer 2 | ECE2019

Assessment of different ti-rads systems using computer-aided detection technology

Chen Kuen-Yuan , Wu Ming-Hsun , Chen Chiung-Nien , Chen Argon

Aims: Different guidelines of Thyroid Imaging, Reporting, and Data System (TI-RADS) have been published to determine whether FNAC is required. Most of the guidelines recommended observation for nodules less than one centimeter and FNAC for nodule larger than two centimeters. In this study, we focus on the management of nodules size between one and two centimeters. We aim to evaluate the different guidelines on the treatment of thyroid nodules with the computer-aided detection ...