Searchable abstracts of presentations at key conferences in endocrinology
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21st European Congress of Endocrinology

Lyon, France
18 May 2019 - 21 May 2019

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18-21 May 2019, Lyon, France

Poster Presentations

Environment, Society and Governance

ea0063p994 | Environment, Society and Governance | ECE2019

Effect of octyl-phenol and bisphenol A on calcium signaling in cardiomyocyte differentiation of mouse embryonic stem cells

Lee Jae-Hwan , Go Seon Myeong , Yoo Yeong-Min , Jeung Eui-Bae

Endocrine-disrupting chemicals (EDCs) have similar structures with steroids hormones, which can interfere with hormone synthesis and normal physiological functions of male and female reproductive organs. Sex steroid hormones influence calcium signaling of the cardiac muscle in early embryo development. Progesterone (P4) has been reported to reduce blood pressure. To confirm the effect of P4, octyl-phenol (OP) and bisphenol A (BPA) on early differentiation of mouse embryonic st...

ea0063p995 | Environment, Society and Governance | ECE2019

Second-phase validation of developmental toxicity test using embryoid body’s area

Lee Jae-Hwan , Park Seon Mi , Jung Eui-Man , Jeung Eui-Bae

The embryoid body test (EBT) is a developmental toxicity test method that assesses the half inhibitory concentrations of substances in the area of embryoid bodies (EBs), and in the viability of mouse embryonic stem cells (ESCs) and fibroblasts (3T3 cells). In the previous pre-validation study evaluated the predictive accuracy of the EBT using 26 coded test substances and highly accurate (above 80%) when substances were classified using the predictive model. EBT used two same e...

ea0063p996 | Environment, Society and Governance | ECE2019

When do Greeks seek information on obesity and diet?

Ilias Ioannis , Venaki Evangelia , Kakoulidis Ioannis , Michou Aikaterini , Linardi Anastasia , Koukkou Eftychia

Introduction: Internet users perform health information-seeking searches triggered by personal symptoms or diseases. Such searches may provide information - albeit indirectly - on disease patterns and epidemiology (PLoS One. 2014, 9:e109583, PNAS 2016; 113:6689-94). It was recently reported that in Asia (more particularly in Taiwan), online searches for obesity and diet (indirectly reflecting corresponding health-seeking behaviors) at times of financial crisis (recession) were...

ea0063p997 | Environment, Society and Governance | ECE2019

Influence of structure education program on glycemic control of patients with type 1 diabetes and depression

Popovic-Pejicic Snježana , Figurek Andreja , Jankovic-Pejicic Anja

Introduction: In patients with type 1 diabetes (T1D), depression increases the risk for persistent hyperglycemia, diabetes complications and mortality. Most results demonstrated that depression is associated with nearly all important medical and psychosocial outcome parameters of T1D. Also, it has been demonstrated that poor diabetes self-care can result from patientsÂ’ lack of knowledge or existing psychosocial issues, primarily depression. The aim of the study was to det...

ea0063p998 | Environment, Society and Governance | ECE2019

Evaluation of patient satisfaction in an endocrinology and metabolism diseases center

Ozdemir Didem , Dirikoc Ahmet , Ersoy Reyhan , Cakir Bekir

Introduction: In our country, some health institutions are allowed to constitute additional service buildings/centers in order to increase the accessibility to outpatient services and decrease the crowdiness in hospitals. We aimed to investigate the satisfaction of the patients evaluated in our endocrinology and metabolism diseases center-ENDOOTEM (Endocrinology-Nuclear Medicine-Diabetes-Obesity-Osteoporosis-Thyroid Diagnosis and TreatmentCenter)- which serves as a part of our...

ea0063p999 | Environment, Society and Governance | ECE2019

Low doses of persistent organic pollutants (PFOA and PCB153) increase the tumor aggressiveness of hormone-dependent cancer cells

Charazac Aurelie , Hinault Charlotte , Bost Frederic , Clavel Stephan , Chevalier Nicolas

Persistent organic pollutants (POPs) are lipophilic chemicals that chronically accumulate in the body during lifetime from fetal life. Some POPs alter the endocrine metabolism and are considered as endocrine disrupting chemicals (EDCs). Human exposure to EDCs, even at low doses, raises some serious concerns for human health because they can participate in hormone-dependent cancer initiation and progression (prostate, breast, testis). These mostly non-metabolizable molecules ar...

ea0063p1000 | Environment, Society and Governance | ECE2019

In vitro effects of the endocrine disruptors DEHP, DBP and BPA on INSL3 receptor (RXFP2)

Suteau Valentine , Gourdin Louis , Briet Claire , Rodien Patrice , Munier Mathilde

Introduction: Epidemiological and In vivo experimental studies reveal reprotoxic effects of endocrine disruptors (phthalates (DBP, DEHP) and bisphenol A (BPA)). An inverse association was found between the concentration of these endocrine disruptors and the concentration of INSL3. INSL3, a relaxine peptide, is involved in reproductive function, via its cognate receptor, RXFP2. The aim of this study was to characterize the involvement of RXFP2 in the effects o...

ea0063p1001 | Environment, Society and Governance | ECE2019

Halogenous derivatives of Bisphenol A inhibit the human FSH receptor activity

Sibilia Paul , Doumas Manon , Gourdin Louis , Briet Claire , Carato Pascal , Rodien Patrice , Munier Mathilde

Numerous epidemiological studies link exposure to Bisphenol A (BPA) to reproductive function anomalies. Our team recently showed that BPA inhibits the action of Follicle Stimulating Hormone (FSH) on its receptor (FSHR). Water decontamination is achieved by chloration, which leads to the formation of chlorinated derivatives of Bisphenol A (ClXBPA), that may be found in natural environments and biological liquids or organs. In the presence of bromine, the formation of...

ea0063p1002 | Environment, Society and Governance | ECE2019

Observational study on the cardio-metabolic effects of a night shift on internists

Bernardi Stella , Toffoli Barbara , Ferretti Tommaso , Francica Morena , Ghirigato Elena , Rovina Matteo , Calabro Veronica , Stenner Elisabetta , Giudici Fabiola , Fabris Bruno

Introduction: Shift work has been associated with increased cardiovascular morbidity and mortality. Several studies have demonstrated that shift work has an effect on cardiovascular and metabolic health. Most of these studies have compared different groups of shift workers to nonshift workers. By contrast, the present work aimed to evaluate the cardio-metabolic effects of night shifts on the same group of internists as they changed type of duty. In particular, we focused on bl...

ea0063p1003 | Environment, Society and Governance | ECE2019

Anthropometric outcomes of shift work in midwives

Jemel Manel , Stambouli Islem , Kandara Hajer , Chebbi Safa , Mansouri Leila , Kammoun Ines

Introduction: The twenty-four hour nature of healthcare demands many nurses and midwives work in shifts. However night work shift is associated with adverse health outcomes like higher risks of obesity; and an unhealthy diet may be a contributing factor. Methods: A descriptive, cross-sectional study, carried out for one month, about midwives in delivery room in five university hospitals in Tunis. For this population there is no worker on the day but rath...

ea0063p1004 | Environment, Society and Governance | ECE2019

Evaluation of weight and nutritional diaries of students of public schools in a Brazilian town

D'Abronzo Francisco Homero , Ferrari Taina Cristina , Gonzaga Lucas Mandarini , Escano Heitor Castanharo , Guedes Matheus Machado Fleury , Aoki Ricardo Kazuhiro , Vernin Laura Regina Sole , Otsubo Ricardo Hashioka Soler , Zagonel Luciane , Freire Maria Beatriz Sayeg

Between 1970–1975 brazilian children with overweight were 8% and 11%, and obesity 2% and 3% for girls and boys, respectively. In 2008 overweight was 32% and 34%, and obesity 12% and 17% for girls and boys, respectively. In this study we have evaluated the nutritional profile of public school students in our town. A cross sectional observational study was developed in 2017. Mean height (3 determinations) was ascertained in the morning by trained physical educators in 1115 ...

ea0063p1005 | Environment, Society and Governance | ECE2019

Genetic associations of vitamin D increase after supplementation

Trummer Olivia , Schweighofer Natascha , Haudum Christoph W , Trummer Christian , Lerchbaum Elisabeth , Pieber Thomas R , Colantonio Caterina , Kolesnik Ewald , Schmidt Albrecht , Pieske Burkert , Obermayer-Pietsch Barbara

Apart from the crucial effects of vitamin D on bone health, vitamin D deficiency has been associated with various chronic conditions such as metabolic or reproductive disturbances. The polycystic ovary syndrome (PCOS) represents the most common endocrine disorder among women of reproductive age. Women affected by PCOS frequently suffer from oligo- or anovulation as well as from obesity and insulin resistance. There is accumulating evidence showing an association of vitamin D s...

ea0063p1006 | Environment, Society and Governance | ECE2019

Telemedicine in the management of acromegalic patients

Sindaco Giulia Del , Sala Elisa , Carosi Giulia , Verrua Elisa , Serban Andreea Liliana , Ferrante Emanuele , Arosio Maura , Mantovani Giovanna

Background: In acromegalic patients, quality of life reduction and neuropsychological impairment are common, in addition to well-known complications related to the pituitary adenoma and to the GH/IGF-I excess. Acromegalic patients need a lot of outpatient visits and a multidisciplinary approach during the management of the disease and its comorbidities. Aim of the project is to analyze the role of an electronic health device (eHD) with remote monitoring in management of acrome...

ea0063p1007 | Environment, Society and Governance | ECE2019

Seasonality of hyponatremia in hospitalized medical patients – data from a nationwide cohort study

Sailer Clara O , Kutz Alexander , Ebrahimi Fahim , Wagner Ulrich , Schuetz Philipp

Introduction: Hyponatremia is the most prevalent electrolyte disturbance in hospitalized patients. Seasonal variation with higher incidence of profound hyponatremia during summer months has been described for patients in the emergency department setting. Whether this observation is also true among medical inpatients is unknown. This study aimed at analyzing the seasonal incidence of hyponatremia as well as sex and age specific differences among medical inpatients.<p class=...