Searchable abstracts of presentations at key conferences in endocrinology
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21st European Congress of Endocrinology

Lyon, France
18 May 2019 - 21 May 2019

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18-21 May 2019, Lyon, France

Symposia

Late Breaking Session

ea0063s25.2 | Late Breaking Session | ECE2019

Levothyroxine in preconception women with thyroid peroxidase antibodies

Smith Rima

Background: Thyroid peroxidase antibodies are associated with increased risk of miscarriage and preterm birth, even when thyroid function is normal. Small trials indicate levothyroxine could reduce such adverse outcomes.Methods: We conducted a double-blind, placebo-controlled trial to investigate whether levothyroxine treatment would increase live birth rates among euthyroid women with thyroid peroxidase antibodies and a history of miscarriage or inferti...

ea0063s25.3 | Late Breaking Session | ECE2019

Maternal smoking and high BMI disrupt thyroid gland development

Filis Panagiotis

Around half of expectant mothers worldwide are overweight or obese and 20% smoke. Exposure to such factors during fetal life is linked to diseases including obesity, cardiovascular disease, and behavioural disorders. Because thyroid hormones control fetal metabolism, cardiac output and brain development, altered fetal thyroid signalling can contribute to future disease. We examined the impact of maternal smoking and overweight/obese (body mass index, BMI, ≥25) on the thy...