Several lifestyle modification strategies have been suggested to prevent lifestyle-related diseases. However, the situation may be different for health check participants and outpatients. This study aimed to determine suitable lifestyle modification strategies to prevent diabetes in individuals who participated in a medical health check using retrospective cohort study. Individuals who participated in a medical health check in Fukuyama, Japan every year from 20112015 were investigated. Laboratory data between 2011 and 2015 were compared and the association between current lifestyle and onset of diabetes in the next 5 years was assessed via Cox proportional hazard model, controlling for age, sex, and body mass index (BMI). Disease onset was defined as the year of starting relevant medications. BMI was not different between 2011 and 2015. By contrast, waist circumference, systolic blood pressure, diastolic blood pressure, plasma glucose, and hemoglobin A1c levels were significantly higher in 2015 compared with those of 2011. Onset of diabetes was related to current smoking. In addition, eating quickly was relevant to the onset of diabetes in the next 5 years. Medical professionals generally use less calories and more exercise as advise to patients with lifestyle-related diseases. However, recommended lifestyle modification for those undergoing health checks and those in an outpatient-setting should be modified as appropriate, as they may have different characteristics from those who already have lifestyle-related diseases.
18 - 21 May 2019
European Society of Endocrinology