ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Endocrine Abstracts (2019) 63 P132 | DOI: 10.1530/endoabs.63.P132

Association of serum lipid profile and insulin resistance in polycystic ovary syndrome (PCOs) women in Ahvaz, Iran

Homeira Rashidi, Mina Tafazoli, Mohammad Taha Jalali & Armaghan Moravej Aleali

Diabetes Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Republic of Islamic.

Polycystic ovary syndrome is a common endocrine disorder in women was associated with lipid disorders with increased risk of cardiovascular disease and obesity are associated. This study aimed to compare the lipid profile and fasting plasma glucose levels, insulin resistance in women with polycystic ovary syndrome is done with the control group.

Methods: This case–control study on 153 women with PCOS and 449 healthy control subjects from 4 cities in the province of Khuzestan) was performed. Serum lipids, fasting plasma glucose and serum insulin levels associated with BMI, HOMA IR, Lipid Accumulation Product Index and Body Adiposity Index in the two groups were compared using appropriate statistical tests.

Results: Prevalence of low HDL and total cholesterol> 200 in women with polycystic ovary higher than the control group (respectively P=0.032 and P=0.001). Average levels of total cholesterol, triglycerides, HDL, LDL, glucose and indicators HOMA IR, LAP and BA in between the two groups showed no significant difference. In PCOs women with BMI <25 and BMI between 25 and 30, mean total cholesterol was higher than the control group, the PCOs subjects with BMI> 30 had average triglycerides and glucose higher than women in the control group respectively P=0.029, P=0.010.

Conclusion: The level of triglycerides and glucose in obese women with polycystic ovary syndrome were more than healthy women. PCOs non-obese women had a total cholesterol level higher than healthy women.

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