ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Endocrine Abstracts (2019) 63 P987 | DOI: 10.1530/endoabs.63.P987

Epidemiological, clinical and biochemical characteristics of metabolic syndrome in adults living in South of Tunisia

Ghazi Chabchoub1,2, Imene Gargouri3, Faten Hadj Kacem3, Nadia Charfi3, Mouna Mnif3, Leila Keskes1 & Mohamed Abid3


1Laboratoire de génétique Moléculaire Humaine, Faculté de medecine, Sfax, Tunisia; 2La Caisse National Assurance Maladie, Sfax, Tunisia; 3Service d’endocrinologie, Centre Hospitalo Universitaire, Sfax, Tunisia.


The metabolic syndrome (MetS) is a constellation of physiological and biochemical abnormalities characterized by obesity, hyperglycaemia, elevated triglycerides and decreases in high density lipoprotein cholesterol (HDL-C), and hypertension. The MetS promotes atherosclerosis, and increases the risk of developing diabetes and cardiovascular disease (CVD), as well as rates of mortality. Thus, it has become one of the major public health challenges worldwide. In Tunisia, few studies have described the prevalence of MetS and its related factors, hence restricting the quality of information available on the magnitude of this problem in the country. We studied a retrospective cohort of 602 patients explored in the department of Endocrinology of Sfax (south of Tunisia). The MetS was defined according to the National Cholesterol Education Program–Adult Treatment PanelIII. 66% of patients have a medium level education. The mean age was 58.6 years, sex ratio 3 F/1M, average weight was 82±16 kg, waist circumference was 110±11 cm, and body mass index was 33±5.7 kg/m2. Hyperglycemia was the most common found in 94.7%. Arterial hypertension and hypertriglyceridemia were less frequent (83% and 70.1% respectivly). 89.7% of our patients have type 2 diabetes. Cardiovascular complications was found in 26% mainly coronary insufficiency in 18% followed by stroke, myocardial infractus and artheritis (7%, 6% and 5% respectivly). 1% of women bave polycystic ovary syndrome.Characteristic features of MetS in patients seen in south Tunisia were found to be similar to those described in the literature. Other more large-scale representative studies would be useful to establish the epidemiology of MetS in Tunisia.

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