Endocrine Abstracts

Background: Children and young people with type-1 diabetes (T1D) have excess all-cause hospital admissions, particularly younger children with lower socioeconomic status. Education on managing alcohol is provided to teenagers with T1D in paediatric clinics, but its effectiveness is unknown. We compared the risk of alcohol-related hospital admissions (ARHA) in young people with childhood-onset T1D with the general population for the same birth years.Metho...

Introduction: Many children with Type 1 Diabetes (T1D) and their parents/carers anecdotally report poor sleep quality. This is particularly problematic in patients experiencing frequent hypoglycaemia despite intensive blood glucose monitoring (BGM). Continuous glucose monitoring (CGM) overcomes some of the burdens of BGM and can reduce overnight hypoglycaemia.Objectives: This pilot study explored the impact of CGM on sleep quality in children and adolesc...

Introduction: Effective transition care is vital to empower young people (YP) to optimally self-manage their diabetes. National data highlights the concern regarding poorer care outcomes due to lower completion of annual care processes and higher rates of DKA whilst transitioning to adult care. The Children and Young People’s Diabetes Team provides care for 170 YP aged 16–19 years. In April 2017, 19% of this age group had a HbA1c <58 mmol/mol, significantly lower...

Introduction: Evidence is currently limited regarding the management of abnormal lipid profiles in children and young people (CYP) with Type 1 Diabetes Mellitus (T1DM). ISPAD recommend monitoring every five years and statin use to maintain LDL cholesterol <3.4 mmol/L1. Guidance is specific to LDL. NICE guidelines do no recommend routine screening for CYP with T1DM.Methodology: We reviewed all lipid profiles (including cholesterol, triglyce...

Background: Suboptimal adherence to insulin treatment is a main issue in adolescents with type 1 diabetes (T1D). However, to date, there are no available data on adherence to adjunct non-insulin medications in this population. The aims of this study were to assess adherence to ACE inhibitors and statins and explore potential determinants in adolescents with T1D in the context of a clinical trial.Methods: 443 adolescents (aged 10–16 years) were recru...

Introduction: Most children & young people (CYP) with symptoms of type 1 diabetes (T1D) tend to present to primary care. Delayed diagnosis is common and is associated with a risk of developing diabetic ketoacidosis (DKA). The prevalence of DKA at diagnosis over the last 20 years remains unchanged despite current NICE guidance and Diabetes Delivery Plans which promote prompt diagnosis of T1D. The aim of this QI initiative was to develop effective pathways to facilitate earl...

Background: The incidence of Paediatric type 2 diabetes is increasing, especially in areas of deprivation.Aim: To describe the cohort of CYP with T2D in Royal London Hospital over the period 2009–2018.Methods: Retrospective analysis of patient cohort.Results: Number of new patients doubled from 2.6/year in 2009–2013 to 5.3/year in 2014–2018. Prevalence in our cohort is 7.5% (national average of...

Introduction: Children with type 1 diabetes mellitus (T1DM) are at increased risk of being overweight. Being overweight could be related to insulin requirements, female gender, and duration of diabetes. The aim of this study is to examine the Body Mass Index (BMI) of children and young people with T1DM at the Children’s Hospital for Wales and explore co-factors that may contribute to risk.Methods: A retrospective review of all patients with T1DM att...

Introduction: Although not directly inherited, genetics play a significant role in the chances of developing Type1 Diabetes (T1DM), yielding a risk of 2–40% depending on the first degree relative (FDR) affected. T1DM is a self-managed condition in which education and patient/carer engagement are key. We had noted cases of poor engagement and glycaemic control in our patients with a FDR with T1DM but found a paucity of literature examining this relationship.<p class="a...