Endocrine Abstracts

Background: The incidence of type 2 diabetes in childhood in the UK is increasing. It is often an aggressive disease associated with poor health outcomes. Despite this, there is little formal training and evidence based guidance.Objectives and method: A questionnaire was sent to each paediatric diabetes unit in England and Wales, evaluating variation in practice, training and confidence in the management of type 2 diabetes.Results:...

Background: In the UK, the use of insulin pump therapy in children with Type 1 diabetes is increasing. Many studies have investigated the effectiveness of this treatment in improving biomedical outcomes and quality of life measures. However, few studies have explored the perspectives of children themselves on their use of pump therapy, particularly in the pre-adolescent age group. This study focussed on primary school aged children and aimed to explore in depth how they experi...

Introduction: The successful prevention of type 1 diabetes (T1D) is a major clinical goal. The pathogenesis is multifactorial, with genetic and environmental influences that lead to a break in immune tolerance toward pancreatic beta cells. Through a number of prospective cohort studies, it is now understood that the presence of two or more diabetes-associated autoantibodies is highly predictive of future T1D diagnosis. In addition to the genetic rationale (insulin gene sequenc...

Introduction: Type 1 diabetes (T1D) is a lifelong condition affecting over 29 000 children in the United Kingdom, the majority of whom are in full time education. Both hypoglycaemia and hyperglycaemia have been shown to impact the young person’s overall school performance and learning capacity. During exams, children and young people (CYP) with T1D have the additional stress of managing their diabetes appropriately, and therefore require special provisions. Currently, the...

Background: In type 1 diabetes (T1D), optimal glycaemic control requires intensive self-management to reduce the risk of complications. While routine downloading and review of blood glucose data is part of clinical practice of healthcare providers in an outpatient setting, patients and families are also educated, advised and encouraged to regularly download and review blood glucose data at home in order to make adjustments to insulin dosing for carbohydrate intake and insulin ...