Endocrine Abstracts

Autoimmune endocrine diseases such as type 1 diabetes and autoimmune adrenal insufficiency (Addison’s disease) are disorders that often aggregate in families. Despite being universally lethal before the 20th century, the predisposing genetic variants have remained in the population, probably conferring advantages even at the price of an enhanced risk of developing autoimmunity. With carefully phenotyped patients and geographically matched controls, strong signals can be ...

Olle Kämpe is professor and senior consultant in endocrinology at the Karolinska Institutet in Stockholm, Sweden. He holds the Torsten and Ragnar Söderberg endowment professorship in clinical endocrinology since 2014 and was before that professor of molecular medicine at Uppsala University between 1999 and 2014. He is fellow of the Royal Swedish Academy of Sciences (www.kva.se/en), and member of the Nobel Assembly at the Karolinsk...